Incorporating a New Summary Statistic into the Min–Max Approach: A Min–Max–Median, Min–Max–IQR Combination of Biomarkers for Maximising the Youden Index

Incorporating a New Summary Statistic into the Min–Max Approach: A Min–Max–Median, Min–Max–IQR Combination of Biomarkers for Maximising the Youden Index

Linearly combining multiple biomarkers is a common practice that can provide a better diagnostic performance. When the number of biomarkers is sufficiently high, a computational burden problem arises. Liu et al. proposed a distribution-free approach (min–max approach) that linearly combines the mini...

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Bibliographic Details
Main Authors: Rocío Aznar-Gimeno, Luis M. Esteban, Gerardo Sanz, Rafael del-Hoyo-Alonso, Ricardo Savirón-Cornudella
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Mathematics
Subjects:
linear combination
biomarkers
classification
Youden index
summary statistic
min–max approach
Online Access:https://www.mdpi.com/2227-7390/9/19/2497

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