Early life stress as a risk factor for substance use disorders: Clinical and neurobiological substrates

Early life stress as a risk factor for substance use disorders: Clinical and neurobiological substrates

Background: Early Life Stress (ELS) can profoundly influence an individual′s genotype and phenotype. Effects of ELS can manifest in the short-term, late life and even in subsequent generations. ELS activate corticotrophin releasing factor (CRF); CRF influences drug seeking and addiction. The aim of...

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Bibliographic Details
Main Authors:	Sajoy Purathumuriyil Varghese, Janitza L Montalvo-Ortiz, John G Csernansky, Rodney I Eiger, Amy A Herrold, Maju Mathew Koola, Hongxin Dong
Format:	Article
Language:	English
Published:	SAGE Publishing 2015-01-01
Series:	Indian Journal of Psychological Medicine
Subjects:	Corticotrophin-releasing factor early life stress opioid use disorder substance use disorders morphine
Online Access:	http://www.ijpm.info/article.asp?issn=0253-7176;year=2015;volume=37;issue=1;spage=36;epage=41;aulast=Varghese

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