Bacteriophages and the immune system of the macroorganism

Due to the emergence of antibiotic-resistant strains of bacteria in recent years, the treatment and prevention of various infections with bacteriophages have again become an important area of research. However, when using phages for this purpose, it is necessary to take into account the immune respo...

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Bibliographic Details
Main Authors: I. A. Ivanovа, A. A. Trufanova, A. V. Filippenko, I. A. Bespalova, N. D. Omelchenko
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2019-12-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
Online Access:https://microbiol.elpub.ru/jour/article/view/499
Description
Summary:Due to the emergence of antibiotic-resistant strains of bacteria in recent years, the treatment and prevention of various infections with bacteriophages have again become an important area of research. However, when using phages for this purpose, it is necessary to take into account the immune responses of a macroorganism to their introduction. The data about impact of bacterial viruses on the innate and adaptive immunity system of mammals in available literature are few and contradictory. This issue requires further detailed study, especially in the development of new therapeutic and prophylactic biological products based on bacteriophages.
ISSN:0372-9311
2686-7613