Bacteriophages and the immune system of the macroorganism

Due to the emergence of antibiotic-resistant strains of bacteria in recent years, the treatment and prevention of various infections with bacteriophages have again become an important area of research. However, when using phages for this purpose, it is necessary to take into account the immune respo...

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Main Authors: I. A. Ivanovа, A. A. Trufanova, A. V. Filippenko, I. A. Bespalova, N. D. Omelchenko
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2019-12-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
Online Access:https://microbiol.elpub.ru/jour/article/view/499
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author I. A. Ivanovа
A. A. Trufanova
A. V. Filippenko
I. A. Bespalova
N. D. Omelchenko
author_facet I. A. Ivanovа
A. A. Trufanova
A. V. Filippenko
I. A. Bespalova
N. D. Omelchenko
author_sort I. A. Ivanovа
collection DOAJ
description Due to the emergence of antibiotic-resistant strains of bacteria in recent years, the treatment and prevention of various infections with bacteriophages have again become an important area of research. However, when using phages for this purpose, it is necessary to take into account the immune responses of a macroorganism to their introduction. The data about impact of bacterial viruses on the innate and adaptive immunity system of mammals in available literature are few and contradictory. This issue requires further detailed study, especially in the development of new therapeutic and prophylactic biological products based on bacteriophages.
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spelling doaj.art-918950ee9a8c4540b66913cbc881af072022-12-22T04:03:04ZrusCentral Research Institute for EpidemiologyЖурнал микробиологии, эпидемиологии и иммунобиологии0372-93112686-76132019-12-0106798410.36233/0372-9311-2019-6-79-85460Bacteriophages and the immune system of the macroorganismI. A. Ivanovа0A. A. Trufanova1A. V. Filippenko2I. A. Bespalova3N. D. Omelchenko4Federal State Health Institution the Rostov-on-Don Research Institute for Plague Control of the Federal Service on Consumer Rights Protection and Human Welfare SupervisionFederal State Health Institution the Rostov-on-Don Research Institute for Plague Control of the Federal Service on Consumer Rights Protection and Human Welfare SupervisionFederal State Health Institution the Rostov-on-Don Research Institute for Plague Control of the Federal Service on Consumer Rights Protection and Human Welfare SupervisionFederal State Health Institution the Rostov-on-Don Research Institute for Plague Control of the Federal Service on Consumer Rights Protection and Human Welfare SupervisionFederal State Health Institution the Rostov-on-Don Research Institute for Plague Control of the Federal Service on Consumer Rights Protection and Human Welfare SupervisionDue to the emergence of antibiotic-resistant strains of bacteria in recent years, the treatment and prevention of various infections with bacteriophages have again become an important area of research. However, when using phages for this purpose, it is necessary to take into account the immune responses of a macroorganism to their introduction. The data about impact of bacterial viruses on the innate and adaptive immunity system of mammals in available literature are few and contradictory. This issue requires further detailed study, especially in the development of new therapeutic and prophylactic biological products based on bacteriophages.https://microbiol.elpub.ru/jour/article/view/499reviewbacteriophagesimmune systeminnate and specific immunitytherapyprevention
spellingShingle I. A. Ivanovа
A. A. Trufanova
A. V. Filippenko
I. A. Bespalova
N. D. Omelchenko
Bacteriophages and the immune system of the macroorganism
Журнал микробиологии, эпидемиологии и иммунобиологии
review
bacteriophages
immune system
innate and specific immunity
therapy
prevention
title Bacteriophages and the immune system of the macroorganism
title_full Bacteriophages and the immune system of the macroorganism
title_fullStr Bacteriophages and the immune system of the macroorganism
title_full_unstemmed Bacteriophages and the immune system of the macroorganism
title_short Bacteriophages and the immune system of the macroorganism
title_sort bacteriophages and the immune system of the macroorganism
topic review
bacteriophages
immune system
innate and specific immunity
therapy
prevention
url https://microbiol.elpub.ru/jour/article/view/499
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AT iabespalova bacteriophagesandtheimmunesystemofthemacroorganism
AT ndomelchenko bacteriophagesandtheimmunesystemofthemacroorganism