Mild Infections with Multiple Spotted Fever Grouped Rickettsia Species among Forest Rangers with Tick Bites
Tick-borne rickettsiae are increasingly recognized to cause human infections; however, a complete clinical spectrum is lacking. Thus, surveillance study was conducted among forest rangers with tick bites to describe the clinical manifestations. One hundred fifty-nine blood samples were obtained from...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Compuscript Ltd
2023-03-01
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| Series: | Zoonoses |
| Online Access: | https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0010 |
| _version_ | 1797399437373341696 |
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| author | Yong-Xiang Wu Wen-Jun Liang Fang Tang Lan-Fen Jiang Chen-Tao Guo Fei-Xiang Fu Hao Li Wei Liu |
| author_facet | Yong-Xiang Wu Wen-Jun Liang Fang Tang Lan-Fen Jiang Chen-Tao Guo Fei-Xiang Fu Hao Li Wei Liu |
| author_sort | Yong-Xiang Wu |
| collection | DOAJ |
| description | Tick-borne rickettsiae are increasingly recognized to cause human infections; however, a complete clinical spectrum is lacking. Thus, surveillance study was conducted among forest rangers with tick bites to describe the clinical manifestations. One hundred fifty-nine blood samples were obtained from individuals bitten by ticks and 780 tick samples collected in the same endemic region were examined for the presence of Rickettsia . Serum samples were tested for IgM and IgG antibodies against R. heilongjiangensis . Twenty-five (15.7%) individuals were shown to be infected with 5 Rickettsia species, including 14 Candidatus Rickettsia tarasevichiae (CRT), 8 R. raoultii , 1 R. felis , 1 R. heilongjiangensis , and 1 R. massiliae . Five individuals (1 CRT, 1 R. heilongjiangensis , and 3 R. raoultii ) had mild illnesses; the other 20 individuals were asymptomatic. CRT was present in 38.4% (274/713) of I. persulcatus and 6.4% (3/47) of Hae. concinna . R. raoultii was demonstrated in 30.0% (6/20) of D. silvarum and 14.9% (7/17) of Hae. concinna . R. heilongjiangensis was detected in 9.5% (2/21) of D. silvarum and 0.3% (2/713) of I. persulcatus . The clinical manifestations of these rickettsioses were non-specific and differed from traditional features, thus supporting the necessity of wider investigations involving individuals with tick bites to develop an early differential diagnosis. |
| first_indexed | 2024-03-09T01:40:15Z |
| format | Article |
| id | doaj.art-9189c1eb24f0482baa2ec5211a091927 |
| institution | Directory Open Access Journal |
| issn | 2737-7466 2737-7474 |
| language | English |
| last_indexed | 2024-03-09T01:40:15Z |
| publishDate | 2023-03-01 |
| publisher | Compuscript Ltd |
| record_format | Article |
| series | Zoonoses |
| spelling | doaj.art-9189c1eb24f0482baa2ec5211a0919272023-12-08T17:00:42ZengCompuscript LtdZoonoses2737-74662737-74742023-03-013197910.15212/ZOONOSES-2023-0010Mild Infections with Multiple Spotted Fever Grouped Rickettsia Species among Forest Rangers with Tick BitesYong-Xiang WuWen-Jun LiangFang TangLan-Fen JiangChen-Tao GuoFei-Xiang FuHao LiWei LiuTick-borne rickettsiae are increasingly recognized to cause human infections; however, a complete clinical spectrum is lacking. Thus, surveillance study was conducted among forest rangers with tick bites to describe the clinical manifestations. One hundred fifty-nine blood samples were obtained from individuals bitten by ticks and 780 tick samples collected in the same endemic region were examined for the presence of Rickettsia . Serum samples were tested for IgM and IgG antibodies against R. heilongjiangensis . Twenty-five (15.7%) individuals were shown to be infected with 5 Rickettsia species, including 14 Candidatus Rickettsia tarasevichiae (CRT), 8 R. raoultii , 1 R. felis , 1 R. heilongjiangensis , and 1 R. massiliae . Five individuals (1 CRT, 1 R. heilongjiangensis , and 3 R. raoultii ) had mild illnesses; the other 20 individuals were asymptomatic. CRT was present in 38.4% (274/713) of I. persulcatus and 6.4% (3/47) of Hae. concinna . R. raoultii was demonstrated in 30.0% (6/20) of D. silvarum and 14.9% (7/17) of Hae. concinna . R. heilongjiangensis was detected in 9.5% (2/21) of D. silvarum and 0.3% (2/713) of I. persulcatus . The clinical manifestations of these rickettsioses were non-specific and differed from traditional features, thus supporting the necessity of wider investigations involving individuals with tick bites to develop an early differential diagnosis.https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0010 |
| spellingShingle | Yong-Xiang Wu Wen-Jun Liang Fang Tang Lan-Fen Jiang Chen-Tao Guo Fei-Xiang Fu Hao Li Wei Liu Mild Infections with Multiple Spotted Fever Grouped Rickettsia Species among Forest Rangers with Tick Bites Zoonoses |
| title | Mild Infections with Multiple Spotted Fever Grouped Rickettsia Species among Forest Rangers with Tick Bites |
| title_full | Mild Infections with Multiple Spotted Fever Grouped Rickettsia Species among Forest Rangers with Tick Bites |
| title_fullStr | Mild Infections with Multiple Spotted Fever Grouped Rickettsia Species among Forest Rangers with Tick Bites |
| title_full_unstemmed | Mild Infections with Multiple Spotted Fever Grouped Rickettsia Species among Forest Rangers with Tick Bites |
| title_short | Mild Infections with Multiple Spotted Fever Grouped Rickettsia Species among Forest Rangers with Tick Bites |
| title_sort | mild infections with multiple spotted fever grouped rickettsia species among forest rangers with tick bites |
| url | https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2023-0010 |
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