Layer-By-Layer Fabrication of Large and Thick Human Cardiac Muscle Patch Constructs With Superior Electrophysiological Properties

Layer-By-Layer Fabrication of Large and Thick Human Cardiac Muscle Patch Constructs With Superior Electrophysiological Properties

Engineered cardiac tissues fabricated from human induced pluripotent stem cells (hiPSCs) show promise for ameliorating damage from myocardial infarction, while also restoring function to the damaged left ventricular (LV) myocardium. For these constructs to reach their clinical potential, they need t...

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Bibliographic Details
Main Authors: Danielle Pretorius, Asher M. Kahn-Krell, Xi Lou, Vladimir G. Fast, Joel L. Berry, Timothy J. Kamp, Jianyi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
hearts
tissue engineering
layer-by-layer fabrication
stem cell
superior electrophysiology
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.670504/full

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