An Update on the Treatment of Helicobacter Pylori Infection
Helicobacter pylori treatment is becoming a challenge in light of increasing antimicrobial resistance and falling eradication rates. This is a cause for concern based on the complications of H. pylori infection, which include gastric and peptic ulcers, gastric cancer, and mucosa-associated lymphoid...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
European Medical Journal
2015-12-01
|
| Series: | European Medical Journal Gastroenterology |
| Subjects: | |
| Online Access: | http://emjreviews.com/wp-content/uploads/An-Update-on-the-Treatment-of-Helicobacter-Pylori-Infection.pdf |
| _version_ | 1818289896332197888 |
|---|---|
| author | Sinéad Marian Smith |
| author_facet | Sinéad Marian Smith |
| author_sort | Sinéad Marian Smith |
| collection | DOAJ |
| description | Helicobacter pylori treatment is becoming a challenge in light of increasing antimicrobial resistance and falling eradication rates. This is a cause for concern based on the complications of H. pylori infection, which include gastric and peptic ulcers, gastric cancer, and mucosa-associated lymphoid tissue lymphoma. This review discusses recent data assessing the current treatment options for H. pylori infection and the importance of considering the prevalence of antibiotic resistance at a regional level when choosing an appropriate therapy. Alternatives to the standard first-line treatment, such as bismuth and non-bismuth quadruple therapies, are outlined and rescue therapies involving levofloxacin and rifabutin are also reviewed. |
| first_indexed | 2024-12-13T02:19:33Z |
| format | Article |
| id | doaj.art-9191f25b4460459488eb9dd9f01e943e |
| institution | Directory Open Access Journal |
| issn | 2054-6203 |
| language | English |
| last_indexed | 2024-12-13T02:19:33Z |
| publishDate | 2015-12-01 |
| publisher | European Medical Journal |
| record_format | Article |
| series | European Medical Journal Gastroenterology |
| spelling | doaj.art-9191f25b4460459488eb9dd9f01e943e2022-12-22T00:02:48ZengEuropean Medical JournalEuropean Medical Journal Gastroenterology2054-62032015-12-0141101107An Update on the Treatment of Helicobacter Pylori InfectionSinéad Marian Smith0Department of Clinical Medicine, School of Medicine; School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Dublin, Ireland Helicobacter pylori treatment is becoming a challenge in light of increasing antimicrobial resistance and falling eradication rates. This is a cause for concern based on the complications of H. pylori infection, which include gastric and peptic ulcers, gastric cancer, and mucosa-associated lymphoid tissue lymphoma. This review discusses recent data assessing the current treatment options for H. pylori infection and the importance of considering the prevalence of antibiotic resistance at a regional level when choosing an appropriate therapy. Alternatives to the standard first-line treatment, such as bismuth and non-bismuth quadruple therapies, are outlined and rescue therapies involving levofloxacin and rifabutin are also reviewed.http://emjreviews.com/wp-content/uploads/An-Update-on-the-Treatment-of-Helicobacter-Pylori-Infection.pdfantibiotic resistancebismuth quadruple therapyconcomitant therapyHelicobacter pylorihybrid therapysequential therapytriple therapy |
| spellingShingle | Sinéad Marian Smith An Update on the Treatment of Helicobacter Pylori Infection European Medical Journal Gastroenterology antibiotic resistance bismuth quadruple therapy concomitant therapy Helicobacter pylori hybrid therapy sequential therapy triple therapy |
| title | An Update on the Treatment of Helicobacter Pylori Infection |
| title_full | An Update on the Treatment of Helicobacter Pylori Infection |
| title_fullStr | An Update on the Treatment of Helicobacter Pylori Infection |
| title_full_unstemmed | An Update on the Treatment of Helicobacter Pylori Infection |
| title_short | An Update on the Treatment of Helicobacter Pylori Infection |
| title_sort | update on the treatment of helicobacter pylori infection |
| topic | antibiotic resistance bismuth quadruple therapy concomitant therapy Helicobacter pylori hybrid therapy sequential therapy triple therapy |
| url | http://emjreviews.com/wp-content/uploads/An-Update-on-the-Treatment-of-Helicobacter-Pylori-Infection.pdf |
| work_keys_str_mv | AT sineadmariansmith anupdateonthetreatmentofhelicobacterpyloriinfection AT sineadmariansmith updateonthetreatmentofhelicobacterpyloriinfection |