Novel Regulators of the IGF System in Cancer
The insulin-like growth factor (IGF) system is a dynamic network of proteins, which includes cognate ligands, membrane receptors, ligand binding proteins and functional downstream effectors. It plays a critical role in regulating several important physiological processes including cell growth, metab...
Main Authors: | Caterina Mancarella, Andrea Morrione, Katia Scotlandi |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
|
Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/2/273 |
Similar Items
-
Unraveling the IGF System Interactome in Sarcomas Exploits Novel Therapeutic Options
by: Caterina Mancarella, et al.
Published: (2021-08-01) -
Oncofetal protein IGF2BPs in human cancer: functions, mechanisms and therapeutic potential
by: Tian-Yu Zhu, et al.
Published: (2023-06-01) -
Therapeutic Targeting of the IGF Axis
by: Eliot Osher, et al.
Published: (2019-08-01) -
IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling
by: Yosuke Yoneyama, et al.
Published: (2018-04-01) -
The Insulin/IGF system in colorectal cancer development and resistance to therapy
by: Paolo Giovanni Vigneri, et al.
Published: (2015-10-01)