STATINES IN PREVENTION AND TREATMENT OF ATHEROSCLEROSIS CONNECTED DISEASES: EFFICIENCY AND SAFETY
<p>Results of large-scale studies carried out during last 10 years and devoted to the assessment of statines efficiency in prevention of ischemic heart disease (IHD), are analyzed. Decrease in risks of myocardial infarction, instable angina pectoris and mortality by 25-40%, ischemic stroke – b...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2015-12-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | http://www.rpcardio.ru/jour/article/view/354 |
| _version_ | 1797764121312100352 |
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| author | Y. A. Karpov |
| author_facet | Y. A. Karpov |
| author_sort | Y. A. Karpov |
| collection | DOAJ |
| description | <p>Results of large-scale studies carried out during last 10 years and devoted to the assessment of statines efficiency in prevention of ischemic heart disease (IHD), are analyzed. Decrease in risks of myocardial infarction, instable angina pectoris and mortality by 25-40%, ischemic stroke – by 25-30% (CARE, LIPID, WOSCOPS, AFCAPS/TexCAPS, HPS, ASCOT-LLA, CARDS) is demonstrated. Recommendations for statines prescription for primary and secondary prevention of cardiovascular diseases, including IHD and ischemic stroke, are significantly expanded. New goals in holesterol of low density lipoproteid (HLDL) reduction are discussed, aswell as problems of statin treatment safety. The choice of the drug must be based on clinical research data, considering efficiency and safety at long-term use, as well as possibilities of achieving new goal level of HLDL.</p> |
| first_indexed | 2024-03-12T19:51:13Z |
| format | Article |
| id | doaj.art-91948f1ba7ee4594b96a7a70770d651e |
| institution | Directory Open Access Journal |
| issn | 1819-6446 2225-3653 |
| language | English |
| last_indexed | 2024-03-12T19:51:13Z |
| publishDate | 2015-12-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj.art-91948f1ba7ee4594b96a7a70770d651e2023-08-02T03:10:10ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-12-0112485310.1234/1819-6446-2005-2-48-53354STATINES IN PREVENTION AND TREATMENT OF ATHEROSCLEROSIS CONNECTED DISEASES: EFFICIENCY AND SAFETYY. A. Karpov0Российский кардиологичесий научно-производственный комплекс Росздрава, Москва<p>Results of large-scale studies carried out during last 10 years and devoted to the assessment of statines efficiency in prevention of ischemic heart disease (IHD), are analyzed. Decrease in risks of myocardial infarction, instable angina pectoris and mortality by 25-40%, ischemic stroke – by 25-30% (CARE, LIPID, WOSCOPS, AFCAPS/TexCAPS, HPS, ASCOT-LLA, CARDS) is demonstrated. Recommendations for statines prescription for primary and secondary prevention of cardiovascular diseases, including IHD and ischemic stroke, are significantly expanded. New goals in holesterol of low density lipoproteid (HLDL) reduction are discussed, aswell as problems of statin treatment safety. The choice of the drug must be based on clinical research data, considering efficiency and safety at long-term use, as well as possibilities of achieving new goal level of HLDL.</p>http://www.rpcardio.ru/jour/article/view/354Статиныпрофилактикаатеросклерозэффективностьбезопасность |
| spellingShingle | Y. A. Karpov STATINES IN PREVENTION AND TREATMENT OF ATHEROSCLEROSIS CONNECTED DISEASES: EFFICIENCY AND SAFETY Рациональная фармакотерапия в кардиологии Статины профилактика атеросклероз эффективность безопасность |
| title | STATINES IN PREVENTION AND TREATMENT OF ATHEROSCLEROSIS CONNECTED DISEASES: EFFICIENCY AND SAFETY |
| title_full | STATINES IN PREVENTION AND TREATMENT OF ATHEROSCLEROSIS CONNECTED DISEASES: EFFICIENCY AND SAFETY |
| title_fullStr | STATINES IN PREVENTION AND TREATMENT OF ATHEROSCLEROSIS CONNECTED DISEASES: EFFICIENCY AND SAFETY |
| title_full_unstemmed | STATINES IN PREVENTION AND TREATMENT OF ATHEROSCLEROSIS CONNECTED DISEASES: EFFICIENCY AND SAFETY |
| title_short | STATINES IN PREVENTION AND TREATMENT OF ATHEROSCLEROSIS CONNECTED DISEASES: EFFICIENCY AND SAFETY |
| title_sort | statines in prevention and treatment of atherosclerosis connected diseases efficiency and safety |
| topic | Статины профилактика атеросклероз эффективность безопасность |
| url | http://www.rpcardio.ru/jour/article/view/354 |
| work_keys_str_mv | AT yakarpov statinesinpreventionandtreatmentofatherosclerosisconnecteddiseasesefficiencyandsafety |