Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking
Magnetic resonance imaging (MRI) is a promising non-invasive imaging technique that can be safely used to study placental development and function. However, studies of the human placenta performed by MRI are limited by uterine motion and motion in the uterus during MRI remains one of the major limit...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-10-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/10/10/840 |
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| author | Thomas Martin Carla Janzen Xinzhou Li Irish Del Rosario Teresa Chanlaw Sarah Choi Tess Armstrong Rinat Masamed Holden H. Wu Sherin U. Devaskar Kyunghyun Sung |
| author_facet | Thomas Martin Carla Janzen Xinzhou Li Irish Del Rosario Teresa Chanlaw Sarah Choi Tess Armstrong Rinat Masamed Holden H. Wu Sherin U. Devaskar Kyunghyun Sung |
| author_sort | Thomas Martin |
| collection | DOAJ |
| description | Magnetic resonance imaging (MRI) is a promising non-invasive imaging technique that can be safely used to study placental development and function. However, studies of the human placenta performed by MRI are limited by uterine motion and motion in the uterus during MRI remains one of the major limiting factors. Here, we aimed to investigate the characterization of uterine activity during MRI in the second trimester of pregnancy using MRI-based motion tracking. In total, 46 pregnant women were scanned twice (first scan between 14 and 18 weeks and second scan between 19 and 24 weeks), and 20 pregnant subjects underwent a single MRI between 14 and 18 weeks GA, resulting in 112 MRI scans. An MRI-based algorithm was used to track uterine motion in the superior-inferior and left-right directions. Uterine contraction and maternal motion cases were separated by the experts, and unpaired Wilcoxon tests were performed within the groups of gestational age (GA), fetal sex, and placental location in terms of the overall intensity measures of the uterine activity. In total, 22.3% of cases had uterine contraction during MRI, which increased from 18.6% at 14–18 weeks to 26.4% at 19–24 weeks GA. The dominant direction of the uterine contraction and maternal motion was the superior to the inferior direction during early gestation. |
| first_indexed | 2024-03-10T15:31:40Z |
| format | Article |
| id | doaj.art-919844ed217b4653974b6d56fa24666d |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T15:31:40Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-919844ed217b4653974b6d56fa24666d2023-11-20T17:36:09ZengMDPI AGDiagnostics2075-44182020-10-01101084010.3390/diagnostics10100840Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion TrackingThomas Martin0Carla Janzen1Xinzhou Li2Irish Del Rosario3Teresa Chanlaw4Sarah Choi5Tess Armstrong6Rinat Masamed7Holden H. Wu8Sherin U. Devaskar9Kyunghyun Sung10Radiological Sciences, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USADepartment of Obstetrics and Gynecology, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USARadiological Sciences, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USADepartment of Epidemiology, UCLA School of Public Health, Los Angeles, CA 90095, USADepartment of Pediatrics, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USADepartment of Pediatrics, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USARadiological Sciences, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USARadiological Sciences, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USARadiological Sciences, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USADepartment of Pediatrics, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USARadiological Sciences, University of California Los Angeles (UCLA), Los Angeles, CA 90095, USAMagnetic resonance imaging (MRI) is a promising non-invasive imaging technique that can be safely used to study placental development and function. However, studies of the human placenta performed by MRI are limited by uterine motion and motion in the uterus during MRI remains one of the major limiting factors. Here, we aimed to investigate the characterization of uterine activity during MRI in the second trimester of pregnancy using MRI-based motion tracking. In total, 46 pregnant women were scanned twice (first scan between 14 and 18 weeks and second scan between 19 and 24 weeks), and 20 pregnant subjects underwent a single MRI between 14 and 18 weeks GA, resulting in 112 MRI scans. An MRI-based algorithm was used to track uterine motion in the superior-inferior and left-right directions. Uterine contraction and maternal motion cases were separated by the experts, and unpaired Wilcoxon tests were performed within the groups of gestational age (GA), fetal sex, and placental location in terms of the overall intensity measures of the uterine activity. In total, 22.3% of cases had uterine contraction during MRI, which increased from 18.6% at 14–18 weeks to 26.4% at 19–24 weeks GA. The dominant direction of the uterine contraction and maternal motion was the superior to the inferior direction during early gestation.https://www.mdpi.com/2075-4418/10/10/840human pregnancyplacenta MRIuterine contractionmaternal motionMRI motion tracking |
| spellingShingle | Thomas Martin Carla Janzen Xinzhou Li Irish Del Rosario Teresa Chanlaw Sarah Choi Tess Armstrong Rinat Masamed Holden H. Wu Sherin U. Devaskar Kyunghyun Sung Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking Diagnostics human pregnancy placenta MRI uterine contraction maternal motion MRI motion tracking |
| title | Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking |
| title_full | Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking |
| title_fullStr | Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking |
| title_full_unstemmed | Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking |
| title_short | Characterization of Uterine Motion in Early Gestation Using MRI-Based Motion Tracking |
| title_sort | characterization of uterine motion in early gestation using mri based motion tracking |
| topic | human pregnancy placenta MRI uterine contraction maternal motion MRI motion tracking |
| url | https://www.mdpi.com/2075-4418/10/10/840 |
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