Review Paper: Polyphenolic Antioxidants and Neuronal Regeneration
Many studies indicate that oxidative stress is involved in the pathophysiology of neurodegenerative diseases. Oxidative stress can induce neuronal damages, modulate intracellular signaling and ultimately leads to neuronal death by apoptosis or necrosis. To review antioxidants preventive effects o...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Iran University of Medical Sciences
2016-05-01
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| Series: | Basic and Clinical Neuroscience |
| Subjects: | |
| Online Access: | http://bcn.iums.ac.ir/browse.php?mag_id=28&slc_lang=en&sid=1 |
| Summary: | Many studies indicate that oxidative stress is involved in the pathophysiology of neurodegenerative
diseases. Oxidative stress can induce neuronal damages, modulate intracellular signaling and
ultimately leads to neuronal death by apoptosis or necrosis. To review antioxidants preventive
effects on oxidative stress and neurodegenerative diseases we accumulated data from international
medical journals and academic informations' sites. According to many studies, antioxidants
could reduce toxic neuronal damages and many studies confirmed the efficacy of polyphenol
antioxidants in fruits and vegetables to reduce neuronal death and to diminish oxidative stress.
This systematic review showed the antioxidant activities of phytochemicals which play as natural
neuroprotectives with low adverse effects against some neurodegenerative diseases as Parkinson
or Alzheimer diseases. |
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| ISSN: | 2008-126X 2228-7442 |