Review Paper: Polyphenolic Antioxidants and Neuronal Regeneration
Many studies indicate that oxidative stress is involved in the pathophysiology of neurodegenerative diseases. Oxidative stress can induce neuronal damages, modulate intracellular signaling and ultimately leads to neuronal death by apoptosis or necrosis. To review antioxidants preventive effects o...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Iran University of Medical Sciences
2016-05-01
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| Series: | Basic and Clinical Neuroscience |
| Subjects: | |
| Online Access: | http://bcn.iums.ac.ir/browse.php?mag_id=28&slc_lang=en&sid=1 |
| _version_ | 1797283108192518144 |
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| author | Amin Ataie Mohammad Shadifar Ramin Ataee |
| author_facet | Amin Ataie Mohammad Shadifar Ramin Ataee |
| author_sort | Amin Ataie |
| collection | DOAJ |
| description | Many studies indicate that oxidative stress is involved in the pathophysiology of neurodegenerative
diseases. Oxidative stress can induce neuronal damages, modulate intracellular signaling and
ultimately leads to neuronal death by apoptosis or necrosis. To review antioxidants preventive
effects on oxidative stress and neurodegenerative diseases we accumulated data from international
medical journals and academic informations' sites. According to many studies, antioxidants
could reduce toxic neuronal damages and many studies confirmed the efficacy of polyphenol
antioxidants in fruits and vegetables to reduce neuronal death and to diminish oxidative stress.
This systematic review showed the antioxidant activities of phytochemicals which play as natural
neuroprotectives with low adverse effects against some neurodegenerative diseases as Parkinson
or Alzheimer diseases. |
| first_indexed | 2024-03-07T17:25:26Z |
| format | Article |
| id | doaj.art-9198a7fff6b240b78d5d5ccfedc40030 |
| institution | Directory Open Access Journal |
| issn | 2008-126X 2228-7442 |
| language | English |
| last_indexed | 2024-03-07T17:25:26Z |
| publishDate | 2016-05-01 |
| publisher | Iran University of Medical Sciences |
| record_format | Article |
| series | Basic and Clinical Neuroscience |
| spelling | doaj.art-9198a7fff6b240b78d5d5ccfedc400302024-03-02T19:16:35ZengIran University of Medical SciencesBasic and Clinical Neuroscience2008-126X2228-74422016-05-01728190Review Paper: Polyphenolic Antioxidants and Neuronal RegenerationAmin Ataie0Mohammad Shadifar1Ramin Ataee2Cellular and Molecular Research Center, Babol University of Medical Sciences, Babol, Iran.Amol Center, Pasteur Institute of Iran, Amol, Iran.Department of Pharmacology and Toxicology, Pharmaceutical Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran.Many studies indicate that oxidative stress is involved in the pathophysiology of neurodegenerative diseases. Oxidative stress can induce neuronal damages, modulate intracellular signaling and ultimately leads to neuronal death by apoptosis or necrosis. To review antioxidants preventive effects on oxidative stress and neurodegenerative diseases we accumulated data from international medical journals and academic informations' sites. According to many studies, antioxidants could reduce toxic neuronal damages and many studies confirmed the efficacy of polyphenol antioxidants in fruits and vegetables to reduce neuronal death and to diminish oxidative stress. This systematic review showed the antioxidant activities of phytochemicals which play as natural neuroprotectives with low adverse effects against some neurodegenerative diseases as Parkinson or Alzheimer diseases.http://bcn.iums.ac.ir/browse.php?mag_id=28&slc_lang=en&sid=1CurcuminAlzheimerResveratrolOxidative stress |
| spellingShingle | Amin Ataie Mohammad Shadifar Ramin Ataee Review Paper: Polyphenolic Antioxidants and Neuronal Regeneration Basic and Clinical Neuroscience Curcumin Alzheimer Resveratrol Oxidative stress |
| title | Review Paper: Polyphenolic Antioxidants and Neuronal Regeneration |
| title_full | Review Paper: Polyphenolic Antioxidants and Neuronal Regeneration |
| title_fullStr | Review Paper: Polyphenolic Antioxidants and Neuronal Regeneration |
| title_full_unstemmed | Review Paper: Polyphenolic Antioxidants and Neuronal Regeneration |
| title_short | Review Paper: Polyphenolic Antioxidants and Neuronal Regeneration |
| title_sort | review paper polyphenolic antioxidants and neuronal regeneration |
| topic | Curcumin Alzheimer Resveratrol Oxidative stress |
| url | http://bcn.iums.ac.ir/browse.php?mag_id=28&slc_lang=en&sid=1 |
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