A liposomal carbohydrate vaccine, adjuvanted with an NKT cell agonist, induces rapid and enhanced immune responses and antibody class switching

A liposomal carbohydrate vaccine, adjuvanted with an NKT cell agonist, induces rapid and enhanced immune responses and antibody class switching

Abstract Background Congenital disorders of glycosylation (CDGs) are genetic diseases caused by gene defects in glycan biosynthesis pathways, and there is an increasing number of patients diagnosed with CDGs. Because CDGs show many different clinical symptoms, their accurate clinical diagnosis is ch...

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Bibliographic Details
Main Authors: Ji-Xiang Jia, Sen-Lin Peng, Ndayambaje Yvan Kalisa, Qiang Chao, Zhifang Zhou, Xiao-Dong Gao, Ning Wang
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Nanobiotechnology
Subjects:
Carbohydrate vaccine
Liposome nanoparticles
Adjuvant
Congenital disorders of glycosylation
Antibody class switching
Online Access:https://doi.org/10.1186/s12951-023-01927-x

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