Gene profiling of Toll-like receptor signalling pathways in neutrophils of patients with acute-on-chronic liver failure
Abstract Objectives Toll-like receptors (TLRs) on neutrophils play a crucial role in detecting pathogens and organ/tissue injury in acute-on-chronic liver failure (ACLF). However, little is known about the exact mechanisms and potential signalling pathways. The aim of this study was to investigate a...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-11-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-021-03135-3 |