MORPHOLOGY OF ISCHEMIC INJURY OF LIVER ALLOGRAFT ACCORDING TO BIOPSIES RESEARCH
The aim of our work is to develop diagnostic criteria of liver ischemic injury according to needle biopsies of liver allograft using light microscopy. We studied 45 zero liver biopsies from cadaver donors with diagnosed brain death and 16 needle biopsies of liver allograft from 12 recipients 1 hour...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2010-06-01
|
| Series: | Vestnik Transplantologii i Iskusstvennyh Organov |
| Subjects: | |
| Online Access: | https://journal.transpl.ru/vtio/article/view/320 |
| _version_ | 1797872083254902784 |
|---|---|
| author | L. V. Shkalova M. G. Minina N. P. Mogeiko I. M. Iljinsky Y. G. Moysyuk O. M. Tsirulnikova S. V. Gautier |
| author_facet | L. V. Shkalova M. G. Minina N. P. Mogeiko I. M. Iljinsky Y. G. Moysyuk O. M. Tsirulnikova S. V. Gautier |
| author_sort | L. V. Shkalova |
| collection | DOAJ |
| description | The aim of our work is to develop diagnostic criteria of liver ischemic injury according to needle biopsies of liver allograft using light microscopy. We studied 45 zero liver biopsies from cadaver donors with diagnosed brain death and 16 needle biopsies of liver allograft from 12 recipients 1 hour up to 1 month after operation. Grading to three stages of ischemic injury in liver allograft is based on clinical and morphological criteria. Ischemic injury of liver allograft is an acute alterative-inflammatory process i.e. there are hepatocyte degeneration and necrosis with following inflammation (exudation with edema, hemorrhage, neutrophil infiltration). In case of favorable outcome ischemic injury of liver allograft is a reversible process. |
| first_indexed | 2024-04-10T00:54:23Z |
| format | Article |
| id | doaj.art-919c3e8feab54ad792c040aaf066cdea |
| institution | Directory Open Access Journal |
| issn | 1995-1191 |
| language | Russian |
| last_indexed | 2024-04-10T00:54:23Z |
| publishDate | 2010-06-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Vestnik Transplantologii i Iskusstvennyh Organov |
| spelling | doaj.art-919c3e8feab54ad792c040aaf066cdea2023-03-13T10:37:20ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912010-06-01123162310.15825/1995-1191-2010-3-16-23263MORPHOLOGY OF ISCHEMIC INJURY OF LIVER ALLOGRAFT ACCORDING TO BIOPSIES RESEARCHL. V. Shkalova0M. G. Minina1N. P. Mogeiko2I. M. Iljinsky3Y. G. Moysyuk4O. M. Tsirulnikova5S. V. Gautier6Federal State Institution Volga Regional Medical Center of Federal Bio-Medical Agency, Nizhny NovgorodMoscow coordinating centre of organ donationAcademician V.I. Schumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Schumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Schumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Schumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Schumakov Federal Research Center of Transplantology and Artificial Organs, MoscowThe aim of our work is to develop diagnostic criteria of liver ischemic injury according to needle biopsies of liver allograft using light microscopy. We studied 45 zero liver biopsies from cadaver donors with diagnosed brain death and 16 needle biopsies of liver allograft from 12 recipients 1 hour up to 1 month after operation. Grading to three stages of ischemic injury in liver allograft is based on clinical and morphological criteria. Ischemic injury of liver allograft is an acute alterative-inflammatory process i.e. there are hepatocyte degeneration and necrosis with following inflammation (exudation with edema, hemorrhage, neutrophil infiltration). In case of favorable outcome ischemic injury of liver allograft is a reversible process.https://journal.transpl.ru/vtio/article/view/320liver allograftischemic injurymorphology |
| spellingShingle | L. V. Shkalova M. G. Minina N. P. Mogeiko I. M. Iljinsky Y. G. Moysyuk O. M. Tsirulnikova S. V. Gautier MORPHOLOGY OF ISCHEMIC INJURY OF LIVER ALLOGRAFT ACCORDING TO BIOPSIES RESEARCH Vestnik Transplantologii i Iskusstvennyh Organov liver allograft ischemic injury morphology |
| title | MORPHOLOGY OF ISCHEMIC INJURY OF LIVER ALLOGRAFT ACCORDING TO BIOPSIES RESEARCH |
| title_full | MORPHOLOGY OF ISCHEMIC INJURY OF LIVER ALLOGRAFT ACCORDING TO BIOPSIES RESEARCH |
| title_fullStr | MORPHOLOGY OF ISCHEMIC INJURY OF LIVER ALLOGRAFT ACCORDING TO BIOPSIES RESEARCH |
| title_full_unstemmed | MORPHOLOGY OF ISCHEMIC INJURY OF LIVER ALLOGRAFT ACCORDING TO BIOPSIES RESEARCH |
| title_short | MORPHOLOGY OF ISCHEMIC INJURY OF LIVER ALLOGRAFT ACCORDING TO BIOPSIES RESEARCH |
| title_sort | morphology of ischemic injury of liver allograft according to biopsies research |
| topic | liver allograft ischemic injury morphology |
| url | https://journal.transpl.ru/vtio/article/view/320 |
| work_keys_str_mv | AT lvshkalova morphologyofischemicinjuryofliverallograftaccordingtobiopsiesresearch AT mgminina morphologyofischemicinjuryofliverallograftaccordingtobiopsiesresearch AT npmogeiko morphologyofischemicinjuryofliverallograftaccordingtobiopsiesresearch AT imiljinsky morphologyofischemicinjuryofliverallograftaccordingtobiopsiesresearch AT ygmoysyuk morphologyofischemicinjuryofliverallograftaccordingtobiopsiesresearch AT omtsirulnikova morphologyofischemicinjuryofliverallograftaccordingtobiopsiesresearch AT svgautier morphologyofischemicinjuryofliverallograftaccordingtobiopsiesresearch |