Molecular Pathways and Targeted Therapies for Malignant Ovarian Germ Cell Tumors and Sex Cord–Stromal Tumors: A Contemporary Review

Molecular Pathways and Targeted Therapies for Malignant Ovarian Germ Cell Tumors and Sex Cord–Stromal Tumors: A Contemporary Review

Non-epithelial ovarian tumors are heterogeneous and account for approximately 10% of ovarian malignancies. The most common subtypes of non-epithelial ovarian tumors arise from germ cells or sex cord and stromal cells of the gonads. These tumors are usually detected at an early stage, and management...

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Bibliographic Details
Main Authors: Asaf Maoz, Koji Matsuo, Marcia A. Ciccone, Shinya Matsuzaki, Maximilian Klar, Lynda D. Roman, Anil K. Sood, David M. Gershenson
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
non-epithelial ovarian tumors
malignant ovarian germ cell tumors
ovarian sex cord–stromal tumors
targeted therapy
precision medicine
cancer genomics
Online Access:https://www.mdpi.com/2072-6694/12/6/1398

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