Massive retinal gliosis: An unusual case with immunohistochemical study

Massive retinal gliosis (MRG) is a rare, benign intraocular condition that results from the proliferation of well-differentiated glial cells. Immunohistochemically, these cells show positivity for glial fibrillary acid protein (GFAP), neuron specific enolase (NSE), and S-100 protein. We encountered...

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Bibliographic Details
Main Authors:	Sanjay D Deshmukh, Amrut V Ashturkar, Shridhar V Babanagare, Suvarna K Gokhale, Anand A Deshpande
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2011-01-01
Series:	Indian Journal of Ophthalmology
Subjects:	Ahmed glaucoma valve hypotony post-penetrating-keratoplasty glaucoma tube extrusion scleral patch Ranibizumab bevacizumab choroidal neovascular membrane age-related macular degeneration intravitreal injection central macular thickness best corrected visual acuity Intravitreal injection methotrexate pharmacokinetics Contrast sensitivity diabetes glare pupil cycle time Anemia diabetic retinopathy microalbuminuria severity Objective Structured Clinical Examination ophthalmology undergraduate Anisometropia anisometropic amblyopia fusion stereopsis Traumatic cataract Birmingham Eye Trauma Terminology System India cataract surgery Children with learning disability ocular disorders refractive errors special needs Charles Bonnet syndrome dementia hallucinations pregabalin Ocular surface reconstruction Steven-Johnson syndrome superficial keratectomy Choroidal melanoma hard exudates lipid exudation Donor sclera globe rupture scleral patch graft Eyelid Miragel retinal detachment scleral buckle Angiitis Behcet disease neuroretinitis Bevacizumab choroidal neovascularization myopia photodynamic therapy ranibizumab triamcinolone acetonide vascular endothelial growth factor Enucleation immunohistochemistry massive retinal gliosis
Online Access:	http://www.ijo.in/article.asp?issn=0301-4738;year=2011;volume=59;issue=3;spage=246;epage=248;aulast=Deshmukh

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Summary:	Massive retinal gliosis (MRG) is a rare, benign intraocular condition that results from the proliferation of well-differentiated glial cells. Immunohistochemically, these cells show positivity for glial fibrillary acid protein (GFAP), neuron specific enolase (NSE), and S-100 protein. We encountered a case of a 45-year-old female with loss of vision in the left eye. She had a history of trauma to that eye two years ago. Enucleation was carried out, because malignancy was suspected due to retinal calcification. On the basis of light microscopy and immunohistochemistry (IHC) performed on the enucleated eye, it was diagnosed as massive retinal gliosis.
ISSN:	0301-4738 1998-3689

Massive retinal gliosis: An unusual case with immunohistochemical study

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