Automated quality control for genome wide association studies [version 1; referees: 1 approved, 2 approved with reservations]
This paper provides details on the necessary steps to assess and control data in genome wide association studies (GWAS) using genotype information on a large number of genetic markers for large number of individuals. Due to varied study designs and genotyping platforms between multiple sites/project...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2016-07-01
|
Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/5-1889/v1 |
Summary: | This paper provides details on the necessary steps to assess and control data in genome wide association studies (GWAS) using genotype information on a large number of genetic markers for large number of individuals. Due to varied study designs and genotyping platforms between multiple sites/projects as well as potential genotyping errors, it is important to ensure high quality data. Scripts and directions are provided to facilitate others in this process. |
---|---|
ISSN: | 2046-1402 |