Risk factors of mortality among patients with stroke in eastern region of the democratic republic of Congo: a retrospective cohort study

BACKGROUND: Stroke is a condition of public health concern and it’s a major cause of acquired disability. The rapid and adequate management (diagnosis and multidisciplinary care) and keeping cardiovascular risk factors well-controlled can help to reduce the incidence of stroke-related death. The stu...

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Main Authors: Larrey Kasereka Kamabu, Hervé Monka Lekuya, Bienvenu Muhindo Kasusula, Moise Muhindo Valimungighe, Nicole Kavugho Mutimani, Louange Maha Kathaka, Eric Sadiki Butala, Adelard Kalima Nzanzu, Zacharie Tsongo Kibendelwa
Format: Article
Language:English
Published: PAMJ 2020-12-01
Series:PAMJ Clinical Medicine
Subjects:
Online Access: https://www.clinical-medicine.panafrican-med-journal.com/content/article/4/123/pdf/123.pdf
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author Larrey Kasereka Kamabu
Hervé Monka Lekuya
Bienvenu Muhindo Kasusula
Moise Muhindo Valimungighe
Nicole Kavugho Mutimani
Louange Maha Kathaka
Eric Sadiki Butala
Adelard Kalima Nzanzu
Zacharie Tsongo Kibendelwa
author_facet Larrey Kasereka Kamabu
Hervé Monka Lekuya
Bienvenu Muhindo Kasusula
Moise Muhindo Valimungighe
Nicole Kavugho Mutimani
Louange Maha Kathaka
Eric Sadiki Butala
Adelard Kalima Nzanzu
Zacharie Tsongo Kibendelwa
author_sort Larrey Kasereka Kamabu
collection DOAJ
description BACKGROUND: Stroke is a condition of public health concern and it’s a major cause of acquired disability. The rapid and adequate management (diagnosis and multidisciplinary care) and keeping cardiovascular risk factors well-controlled can help to reduce the incidence of stroke-related death. The study aims to identify factors associated with stroke mortality in the Eastern region of the Democratic Republic of Congo. METHODS: This series was retrospectively carried out from 2016 to 2020 in different departments managing stroke patients of the following hospitals of Butembo and Katwa health zones: Katwa Referral Hospital, Kitatumba Referral Hospital, Matanda Hospital, and the Catholic University of Graben Teaching Hospital. Files of patients with the diagnosis of stroke were retrieved and reviewed. The parameters such as socio-demographics, medical history, clinical findings, treatment received, and patients´ mortality outcomes were recorded. The Odds Ratio was used for assessing the risk level attributable to mortality from strokes. Univariate and multivariate analyses were conducted to determine significant predictors of mortality. RESULTS: One hundred and eighty (180) patients with stroke were included. Stroke-related mortality was 57/180 (31.7 %). The factors found to be positively associated with mortality are hemorrhagic stroke (aOR 21.21, 6.2-61.3), reaching hospital (late than 24h aOR 33.8, 16.65-66.6), poor compliance to anti-diabetic medication (aOR 8.46, 3.0-4.3), recurrent stroke (aOR 5.81, 2.0-13.8) poor compliance to antihypertensive (aOR 4.46, 1.4-8.0), and the advanced age >75 years (aOR 6.50, 1.96-21.50). The factor negatively associated with mortality includes being a male (aOR: 0.98, 0.41-2.31). CONCLUSION: Stroke is a common cause of mortality in Butembo. Six management variables remained significant in predicting mortality. These factors, most of which can be modified, should constitute the elements of capacity building by healthcare personnel to significantly reduce this mortality.
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spelling doaj.art-91a94ba3b6924fb3a0afe3e347e4dd672022-12-21T20:25:35ZengPAMJPAMJ Clinical Medicine2707-27972707-27972020-12-01412310.11604/pamj-cm.2020.4.123.2263522635Risk factors of mortality among patients with stroke in eastern region of the democratic republic of Congo: a retrospective cohort studyLarrey Kasereka Kamabu0Hervé Monka Lekuya1Bienvenu Muhindo Kasusula2Moise Muhindo Valimungighe3Nicole Kavugho Mutimani4Louange Maha Kathaka5Eric Sadiki Butala6Adelard Kalima Nzanzu7Zacharie Tsongo Kibendelwa Department of Surgery, Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of Congo Department of Surgery, Neurosurgery, School of Medicine, Makerere University, Kampala, Uganda Department of Internal Medicine, Matanda Hospital, Butembo, Democratic Republic of Congo Health Zone of Butembo, Butembo, Democratic Republic of Congo Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of Congo Department of Obstetrics and Gynecology, Consolata Hospital Mathari, Nyeri Town, Kenya Department of Internal Medicine, Faculty of Medicine, Université Catholique du Graben, Butembo, Democratic Republic of Congo Department of Cardiology and Internal Medicine, Kisangani University, Democratic Republic of Congo BACKGROUND: Stroke is a condition of public health concern and it’s a major cause of acquired disability. The rapid and adequate management (diagnosis and multidisciplinary care) and keeping cardiovascular risk factors well-controlled can help to reduce the incidence of stroke-related death. The study aims to identify factors associated with stroke mortality in the Eastern region of the Democratic Republic of Congo. METHODS: This series was retrospectively carried out from 2016 to 2020 in different departments managing stroke patients of the following hospitals of Butembo and Katwa health zones: Katwa Referral Hospital, Kitatumba Referral Hospital, Matanda Hospital, and the Catholic University of Graben Teaching Hospital. Files of patients with the diagnosis of stroke were retrieved and reviewed. The parameters such as socio-demographics, medical history, clinical findings, treatment received, and patients´ mortality outcomes were recorded. The Odds Ratio was used for assessing the risk level attributable to mortality from strokes. Univariate and multivariate analyses were conducted to determine significant predictors of mortality. RESULTS: One hundred and eighty (180) patients with stroke were included. Stroke-related mortality was 57/180 (31.7 %). The factors found to be positively associated with mortality are hemorrhagic stroke (aOR 21.21, 6.2-61.3), reaching hospital (late than 24h aOR 33.8, 16.65-66.6), poor compliance to anti-diabetic medication (aOR 8.46, 3.0-4.3), recurrent stroke (aOR 5.81, 2.0-13.8) poor compliance to antihypertensive (aOR 4.46, 1.4-8.0), and the advanced age >75 years (aOR 6.50, 1.96-21.50). The factor negatively associated with mortality includes being a male (aOR: 0.98, 0.41-2.31). CONCLUSION: Stroke is a common cause of mortality in Butembo. Six management variables remained significant in predicting mortality. These factors, most of which can be modified, should constitute the elements of capacity building by healthcare personnel to significantly reduce this mortality. https://www.clinical-medicine.panafrican-med-journal.com/content/article/4/123/pdf/123.pdf strokemortalityrisk factorsdemocratic republic of congo
spellingShingle Larrey Kasereka Kamabu
Hervé Monka Lekuya
Bienvenu Muhindo Kasusula
Moise Muhindo Valimungighe
Nicole Kavugho Mutimani
Louange Maha Kathaka
Eric Sadiki Butala
Adelard Kalima Nzanzu
Zacharie Tsongo Kibendelwa
Risk factors of mortality among patients with stroke in eastern region of the democratic republic of Congo: a retrospective cohort study
PAMJ Clinical Medicine
stroke
mortality
risk factors
democratic republic of congo
title Risk factors of mortality among patients with stroke in eastern region of the democratic republic of Congo: a retrospective cohort study
title_full Risk factors of mortality among patients with stroke in eastern region of the democratic republic of Congo: a retrospective cohort study
title_fullStr Risk factors of mortality among patients with stroke in eastern region of the democratic republic of Congo: a retrospective cohort study
title_full_unstemmed Risk factors of mortality among patients with stroke in eastern region of the democratic republic of Congo: a retrospective cohort study
title_short Risk factors of mortality among patients with stroke in eastern region of the democratic republic of Congo: a retrospective cohort study
title_sort risk factors of mortality among patients with stroke in eastern region of the democratic republic of congo a retrospective cohort study
topic stroke
mortality
risk factors
democratic republic of congo
url https://www.clinical-medicine.panafrican-med-journal.com/content/article/4/123/pdf/123.pdf
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