Microwave Radiation Applied to the Synthesis of -butyrolactone Derivatives
Many natural products with a broad spectrum of biological effects bear the g-butyrolactone ring. Given the difficulty in isolating large amounts of butyrolactones from natural sources, interest in synthesizing structural analogs of these compounds and in studying their biological properties has inc...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Universidade Federal de Mato Grosso do Sul
2021-10-01
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| Series: | Orbital: The Electronic Journal of Chemistry |
| Subjects: | |
| Online Access: | https://periodicos.ufms.br/index.php/orbital/article/view/15584 |
| _version_ | 1797946921494511616 |
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| author | Paulo Marcos Donate Hugo Elias Barbosa |
| author_facet | Paulo Marcos Donate Hugo Elias Barbosa |
| author_sort | Paulo Marcos Donate |
| collection | DOAJ |
| description |
Many natural products with a broad spectrum of biological effects bear the g-butyrolactone ring. Given the difficulty in isolating large amounts of butyrolactones from natural sources, interest in synthesizing structural analogs of these compounds and in studying their biological properties has increased. In this review, we summarize the main synthetic methodologies to construct γ-butyrolactone derivatives by using multicomponent processes.
DOI: http://dx.doi.org/10.17807/orbital.v13i4.1657
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| first_indexed | 2024-04-10T21:18:40Z |
| format | Article |
| id | doaj.art-91b091f40fb74a6f9773669842fb51d1 |
| institution | Directory Open Access Journal |
| issn | 1984-6428 |
| language | English |
| last_indexed | 2024-04-10T21:18:40Z |
| publishDate | 2021-10-01 |
| publisher | Universidade Federal de Mato Grosso do Sul |
| record_format | Article |
| series | Orbital: The Electronic Journal of Chemistry |
| spelling | doaj.art-91b091f40fb74a6f9773669842fb51d12023-01-20T10:48:11ZengUniversidade Federal de Mato Grosso do SulOrbital: The Electronic Journal of Chemistry1984-64282021-10-01134Microwave Radiation Applied to the Synthesis of -butyrolactone DerivativesPaulo Marcos Donate0Hugo Elias Barbosa1Universidade de São Paulo - USP-RPUniversidade de São Paulo - USP-RP Many natural products with a broad spectrum of biological effects bear the g-butyrolactone ring. Given the difficulty in isolating large amounts of butyrolactones from natural sources, interest in synthesizing structural analogs of these compounds and in studying their biological properties has increased. In this review, we summarize the main synthetic methodologies to construct γ-butyrolactone derivatives by using multicomponent processes. DOI: http://dx.doi.org/10.17807/orbital.v13i4.1657 https://periodicos.ufms.br/index.php/orbital/article/view/15584gamma-butyrolactonemaculalactonemicrowave-assisted synthesismulticomponent reactionMCRone-pot reaction |
| spellingShingle | Paulo Marcos Donate Hugo Elias Barbosa Microwave Radiation Applied to the Synthesis of -butyrolactone Derivatives Orbital: The Electronic Journal of Chemistry gamma-butyrolactone maculalactone microwave-assisted synthesis multicomponent reaction MCR one-pot reaction |
| title | Microwave Radiation Applied to the Synthesis of -butyrolactone Derivatives |
| title_full | Microwave Radiation Applied to the Synthesis of -butyrolactone Derivatives |
| title_fullStr | Microwave Radiation Applied to the Synthesis of -butyrolactone Derivatives |
| title_full_unstemmed | Microwave Radiation Applied to the Synthesis of -butyrolactone Derivatives |
| title_short | Microwave Radiation Applied to the Synthesis of -butyrolactone Derivatives |
| title_sort | microwave radiation applied to the synthesis of butyrolactone derivatives |
| topic | gamma-butyrolactone maculalactone microwave-assisted synthesis multicomponent reaction MCR one-pot reaction |
| url | https://periodicos.ufms.br/index.php/orbital/article/view/15584 |
| work_keys_str_mv | AT paulomarcosdonate microwaveradiationappliedtothesynthesisofbutyrolactonederivatives AT hugoeliasbarbosa microwaveradiationappliedtothesynthesisofbutyrolactonederivatives |