Viruses and viral proteins
For more than 30 years X-ray crystallography has been by far the most powerful approach for determining the structures of viruses and viral proteins at atomic resolution. The information provided by these structures, which covers many important aspects of the viral life cycle such as cell-receptor r...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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International Union of Crystallography
2014-11-01
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| Series: | IUCrJ |
| Subjects: | |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S205225251402003X |
| _version_ | 1818775507765821440 |
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| author | Nuria Verdaguer Diego Ferrero Mathur R. N. Murthy |
| author_facet | Nuria Verdaguer Diego Ferrero Mathur R. N. Murthy |
| author_sort | Nuria Verdaguer |
| collection | DOAJ |
| description | For more than 30 years X-ray crystallography has been by far the most powerful approach for determining the structures of viruses and viral proteins at atomic resolution. The information provided by these structures, which covers many important aspects of the viral life cycle such as cell-receptor recognition, viral entry, nucleic acid transfer and genome replication, has extensively enriched our vision of the virus world. Many of the structures available correspond to potential targets for antiviral drugs against important human pathogens. This article provides an overview of the current knowledge of different structural aspects of the above-mentioned processes. |
| first_indexed | 2024-12-18T10:58:09Z |
| format | Article |
| id | doaj.art-91b0e18c96fc444fbb5b75f6bf062032 |
| institution | Directory Open Access Journal |
| issn | 2052-2525 |
| language | English |
| last_indexed | 2024-12-18T10:58:09Z |
| publishDate | 2014-11-01 |
| publisher | International Union of Crystallography |
| record_format | Article |
| series | IUCrJ |
| spelling | doaj.art-91b0e18c96fc444fbb5b75f6bf0620322022-12-21T21:10:17ZengInternational Union of CrystallographyIUCrJ2052-25252014-11-011649250410.1107/S205225251402003Xtj5005Viruses and viral proteinsNuria Verdaguer0Diego Ferrero1Mathur R. N. Murthy2Institut de Biología Molecular de Barcelona, CSIC, Parc Científic de Barcelona, Baldiri i Reixac 15, 08028-Barcelona, SpainInstitut de Biología Molecular de Barcelona, CSIC, Parc Científic de Barcelona, Baldiri i Reixac 15, 08028-Barcelona, SpainMolecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, IndiaFor more than 30 years X-ray crystallography has been by far the most powerful approach for determining the structures of viruses and viral proteins at atomic resolution. The information provided by these structures, which covers many important aspects of the viral life cycle such as cell-receptor recognition, viral entry, nucleic acid transfer and genome replication, has extensively enriched our vision of the virus world. Many of the structures available correspond to potential targets for antiviral drugs against important human pathogens. This article provides an overview of the current knowledge of different structural aspects of the above-mentioned processes.http://scripts.iucr.org/cgi-bin/paper?S205225251402003Xbacteriophagesgenome deliveryfusion proteinsRNA-dependent RNA polymerasesviral proteasesviral receptorsviruses |
| spellingShingle | Nuria Verdaguer Diego Ferrero Mathur R. N. Murthy Viruses and viral proteins IUCrJ bacteriophages genome delivery fusion proteins RNA-dependent RNA polymerases viral proteases viral receptors viruses |
| title | Viruses and viral proteins |
| title_full | Viruses and viral proteins |
| title_fullStr | Viruses and viral proteins |
| title_full_unstemmed | Viruses and viral proteins |
| title_short | Viruses and viral proteins |
| title_sort | viruses and viral proteins |
| topic | bacteriophages genome delivery fusion proteins RNA-dependent RNA polymerases viral proteases viral receptors viruses |
| url | http://scripts.iucr.org/cgi-bin/paper?S205225251402003X |
| work_keys_str_mv | AT nuriaverdaguer virusesandviralproteins AT diegoferrero virusesandviralproteins AT mathurrnmurthy virusesandviralproteins |