Time to Recovery from Severe Pneumonia and Its Predictors Among Children 2–59 Months of Age Admitted to Pediatric Ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Ethiopia: Retrospective Cohort Study

Lire Lemma Tirore,1 Desta Erkalo Abame,1 Tagesse Sedoro,1 Dejene Ermias,1 Abinet Arega,1 Tegegn Tadesse,1 Selamu Abose Nadamo2 1Department of Public Health, College of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia; 2Department of Midwifery, College of Medicine and Health Scienc...

Full description

Bibliographic Details
Main Authors: Tirore LL, Abame DE, Sedoro T, Ermias D, Arega A, Tadesse T, Nadamo SA
Format: Article
Language:English
Published: Dove Medical Press 2021-07-01
Series:Pediatric Health, Medicine and Therapeutics
Subjects:
Online Access:https://www.dovepress.com/time-to-recovery-from-severe-pneumonia-and-its-predictors-among-childr-peer-reviewed-fulltext-article-PHMT
_version_ 1819087250130993152
author Tirore LL
Abame DE
Sedoro T
Ermias D
Arega A
Tadesse T
Nadamo SA
author_facet Tirore LL
Abame DE
Sedoro T
Ermias D
Arega A
Tadesse T
Nadamo SA
author_sort Tirore LL
collection DOAJ
description Lire Lemma Tirore,1 Desta Erkalo Abame,1 Tagesse Sedoro,1 Dejene Ermias,1 Abinet Arega,1 Tegegn Tadesse,1 Selamu Abose Nadamo2 1Department of Public Health, College of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia; 2Department of Midwifery, College of Medicine and Health Sciences, Wachemo University, Hossana, EthiopiaCorrespondence: Lire Lemma Tirore Tel +251 916281764Email ganetlemma@gmail.comBackground: Severe pneumonia is still the greatest infectious cause of morbidity and mortality in children under the age of five around the world. Each night spent in the hospital raises the chance of bad drug responses, infections, and ulcers by 0.5%, 1.6%, and 0.5%, respectively. In Southern Ethiopia, as well as the research area, little is known regarding death and recovery time from severe pneumonia and their determinants.Objective: To determine time to recovery from severe pneumonia and its predictors among children 2– 59 months of age admitted to pediatric ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital.Methods: A facility-based retrospective cohort study was conducted among children 2– 59 months of age. Three years’ medical records, from January 2017 to December 2020, were reviewed. A total of 280 children with severe pneumonia were included. In the case of survival time, median was calculated. Kaplan Meier survival curve was used to estimate recovery time from severe pneumonia, and the independent effects of covariates on recovery time were analyzed using multivariable Cox-proportional hazard model.Results: The median time to recovery was 4 days (interquartile range = 3, 5). The incidence rate of recovery was 24.16 per 100 person-days. Underweight (adjusted hazard ratio = 0.56, 95% CI = 0.38– 0.80), age group 12– 35 months (adjusted hazard ratio= 2.0, 95% CI=1.30– 3.30), treatment with ampicillin and gentamicin (adjusted hazard ratio= 0.35, 95% CI: 0.13– 0.80), and antibiotic change (adjusted hazard ratio= 0.34, 95% CI = 0.21– 0.53) were statistically significant predictors of time to recovery from severe pneumonia.Conclusion: The median length of stay in the hospital was short (4 days [interquartile range =3, 5]). Time to recover from severe pneumonia was significantly influenced by being underweight, age, antibiotics administered first, and antibiotic change. Measures such as providing nutritious meals to children and ensuring that underweight children are properly managed should be bolstered.Keywords: time to recovery, severe pneumonia, under 5 children, NEMMCSH
first_indexed 2024-12-21T21:33:09Z
format Article
id doaj.art-91b19dba4a7e466a81ef6f88cb9b344e
institution Directory Open Access Journal
issn 1179-9927
language English
last_indexed 2024-12-21T21:33:09Z
publishDate 2021-07-01
publisher Dove Medical Press
record_format Article
series Pediatric Health, Medicine and Therapeutics
spelling doaj.art-91b19dba4a7e466a81ef6f88cb9b344e2022-12-21T18:49:34ZengDove Medical PressPediatric Health, Medicine and Therapeutics1179-99272021-07-01Volume 1234735767166Time to Recovery from Severe Pneumonia and Its Predictors Among Children 2–59 Months of Age Admitted to Pediatric Ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Ethiopia: Retrospective Cohort StudyTirore LLAbame DESedoro TErmias DArega ATadesse TNadamo SALire Lemma Tirore,1 Desta Erkalo Abame,1 Tagesse Sedoro,1 Dejene Ermias,1 Abinet Arega,1 Tegegn Tadesse,1 Selamu Abose Nadamo2 1Department of Public Health, College of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia; 2Department of Midwifery, College of Medicine and Health Sciences, Wachemo University, Hossana, EthiopiaCorrespondence: Lire Lemma Tirore Tel +251 916281764Email ganetlemma@gmail.comBackground: Severe pneumonia is still the greatest infectious cause of morbidity and mortality in children under the age of five around the world. Each night spent in the hospital raises the chance of bad drug responses, infections, and ulcers by 0.5%, 1.6%, and 0.5%, respectively. In Southern Ethiopia, as well as the research area, little is known regarding death and recovery time from severe pneumonia and their determinants.Objective: To determine time to recovery from severe pneumonia and its predictors among children 2– 59 months of age admitted to pediatric ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital.Methods: A facility-based retrospective cohort study was conducted among children 2– 59 months of age. Three years’ medical records, from January 2017 to December 2020, were reviewed. A total of 280 children with severe pneumonia were included. In the case of survival time, median was calculated. Kaplan Meier survival curve was used to estimate recovery time from severe pneumonia, and the independent effects of covariates on recovery time were analyzed using multivariable Cox-proportional hazard model.Results: The median time to recovery was 4 days (interquartile range = 3, 5). The incidence rate of recovery was 24.16 per 100 person-days. Underweight (adjusted hazard ratio = 0.56, 95% CI = 0.38– 0.80), age group 12– 35 months (adjusted hazard ratio= 2.0, 95% CI=1.30– 3.30), treatment with ampicillin and gentamicin (adjusted hazard ratio= 0.35, 95% CI: 0.13– 0.80), and antibiotic change (adjusted hazard ratio= 0.34, 95% CI = 0.21– 0.53) were statistically significant predictors of time to recovery from severe pneumonia.Conclusion: The median length of stay in the hospital was short (4 days [interquartile range =3, 5]). Time to recover from severe pneumonia was significantly influenced by being underweight, age, antibiotics administered first, and antibiotic change. Measures such as providing nutritious meals to children and ensuring that underweight children are properly managed should be bolstered.Keywords: time to recovery, severe pneumonia, under 5 children, NEMMCSHhttps://www.dovepress.com/time-to-recovery-from-severe-pneumonia-and-its-predictors-among-childr-peer-reviewed-fulltext-article-PHMTtime to recoverysevere pneumoniaunder 5 childrennemmcsh
spellingShingle Tirore LL
Abame DE
Sedoro T
Ermias D
Arega A
Tadesse T
Nadamo SA
Time to Recovery from Severe Pneumonia and Its Predictors Among Children 2–59 Months of Age Admitted to Pediatric Ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Ethiopia: Retrospective Cohort Study
Pediatric Health, Medicine and Therapeutics
time to recovery
severe pneumonia
under 5 children
nemmcsh
title Time to Recovery from Severe Pneumonia and Its Predictors Among Children 2–59 Months of Age Admitted to Pediatric Ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Ethiopia: Retrospective Cohort Study
title_full Time to Recovery from Severe Pneumonia and Its Predictors Among Children 2–59 Months of Age Admitted to Pediatric Ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Ethiopia: Retrospective Cohort Study
title_fullStr Time to Recovery from Severe Pneumonia and Its Predictors Among Children 2–59 Months of Age Admitted to Pediatric Ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Ethiopia: Retrospective Cohort Study
title_full_unstemmed Time to Recovery from Severe Pneumonia and Its Predictors Among Children 2–59 Months of Age Admitted to Pediatric Ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Ethiopia: Retrospective Cohort Study
title_short Time to Recovery from Severe Pneumonia and Its Predictors Among Children 2–59 Months of Age Admitted to Pediatric Ward of Nigist Eleni Mohammed Memorial Comprehensive Specialized Hospital, Hossana, Ethiopia: Retrospective Cohort Study
title_sort time to recovery from severe pneumonia and its predictors among children 2 ndash 59 months of age admitted to pediatric ward of nigist eleni mohammed memorial comprehensive specialized hospital hossana ethiopia retrospective cohort study
topic time to recovery
severe pneumonia
under 5 children
nemmcsh
url https://www.dovepress.com/time-to-recovery-from-severe-pneumonia-and-its-predictors-among-childr-peer-reviewed-fulltext-article-PHMT
work_keys_str_mv AT tirorell timetorecoveryfromseverepneumoniaanditspredictorsamongchildren2ndash59monthsofageadmittedtopediatricwardofnigistelenimohammedmemorialcomprehensivespecializedhospitalhossanaethiopiaretrospectivecohortstudy
AT abamede timetorecoveryfromseverepneumoniaanditspredictorsamongchildren2ndash59monthsofageadmittedtopediatricwardofnigistelenimohammedmemorialcomprehensivespecializedhospitalhossanaethiopiaretrospectivecohortstudy
AT sedorot timetorecoveryfromseverepneumoniaanditspredictorsamongchildren2ndash59monthsofageadmittedtopediatricwardofnigistelenimohammedmemorialcomprehensivespecializedhospitalhossanaethiopiaretrospectivecohortstudy
AT ermiasd timetorecoveryfromseverepneumoniaanditspredictorsamongchildren2ndash59monthsofageadmittedtopediatricwardofnigistelenimohammedmemorialcomprehensivespecializedhospitalhossanaethiopiaretrospectivecohortstudy
AT aregaa timetorecoveryfromseverepneumoniaanditspredictorsamongchildren2ndash59monthsofageadmittedtopediatricwardofnigistelenimohammedmemorialcomprehensivespecializedhospitalhossanaethiopiaretrospectivecohortstudy
AT tadesset timetorecoveryfromseverepneumoniaanditspredictorsamongchildren2ndash59monthsofageadmittedtopediatricwardofnigistelenimohammedmemorialcomprehensivespecializedhospitalhossanaethiopiaretrospectivecohortstudy
AT nadamosa timetorecoveryfromseverepneumoniaanditspredictorsamongchildren2ndash59monthsofageadmittedtopediatricwardofnigistelenimohammedmemorialcomprehensivespecializedhospitalhossanaethiopiaretrospectivecohortstudy