A New Method To Determine <italic toggle="yes">In Vivo</italic> Interactomes Reveals Binding of the <named-content content-type="genus-species">Legionella pneumophila</named-content> Effector PieE to Multiple Rab GTPases

A New Method To Determine <italic toggle="yes">In Vivo</italic> Interactomes Reveals Binding of the <named-content content-type="genus-species">Legionella pneumophila</named-content> Effector PieE to Multiple Rab GTPases

ABSTRACT Legionella pneumophila, the causative agent of Legionnaires’ disease, uses the Dot/Icm type IV secretion system (T4SS) to translocate more than 300 effectors into host cells, where they subvert host cell signaling. The function and host cell targets of most effectors remain unknown. PieE is...

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Bibliographic Details
Main Authors: Aurélie Mousnier, Gunnar N. Schroeder, Charlotte A. Stoneham, Ernest C. So, James A. Garnett, Lu Yu, Steve J. Matthews, Jyoti S. Choudhary, Elizabeth L. Hartland, Gad Frankel
Format: Article
Language:English
Published: American Society for Microbiology 2014-08-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01148-14

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