Elimination of Foreign Sequences in Eukaryotic Viral Reference Genomes Improves the Accuracy of Virome Analysis

Elimination of Foreign Sequences in Eukaryotic Viral Reference Genomes Improves the Accuracy of Virome Analysis

ABSTRACT Widespread in public databases, foreign contaminant sequences pose a substantial obstacle in genomic analyses. Such contamination in viral genome databases is also notorious but more complicated and often causes questionable results in various applications, particularly in virome-based viru...

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Bibliographic Details
Main Authors: Junjie Chen, Yue Sun, Xiaomin Yan, Zilin Ren, Guoshuai Wang, Yuhang Liu, Zihan Zhao, Le Yi, Changchun Tu, Biao He
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mSystems
Subjects:
eukaryotic virome
viral disease diagnosis
host contamination
database contamination
foreign sequences
Online Access:https://journals.asm.org/doi/10.1128/msystems.00907-22

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