Perioperative sleep deprivation activates the paraventricular thalamic nucleus resulting in persistent postoperative incisional pain in mice

Perioperative sleep deprivation activates the paraventricular thalamic nucleus resulting in persistent postoperative incisional pain in mice

BackgroundThe duration of postsurgical pain is closely correlated with perioperative stress. Most patients suffer short-term sleep disorder/deprivation before and/or after surgery, which leads to extended postsurgical pain by an undetermined mechanism. The paraventricular thalamus (PVT) is a critica...

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Bibliographic Details
Main Authors: Lei Li, Huijie Zhang, Zhenli Zheng, Nan Ma, Yidan Zhang, Yaping Liu, Jingjing Zhang, Songxue Su, Weidong Zang, Jinping Shao, Jing Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Neuroanatomy
Subjects:
postsurgical pain
paraventricular thalamic nucleus (PVT)
CaMKIIα neurons
perioperative sleep deprivation
stress
Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2022.1074310/full

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