THE ETHIOPATOGENESIS AND THE ANALYSIS OF AN ANTIBIOTIC TREATMENT OF A SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROME

Article is attempt of the critical analysis of modern approaches to treatment of a small intestine bacterial overgrowth syndrome (SIBO). SIBO now is one of the major problems in gastroenterology. At the same time, the bacterial overgrowth is cause and consequence of many diseases of digestive system...

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Main Authors: V. L. Martynov, A. Kh. Khairdinov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2015-06-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/171
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author V. L. Martynov
A. Kh. Khairdinov
author_facet V. L. Martynov
A. Kh. Khairdinov
author_sort V. L. Martynov
collection DOAJ
description Article is attempt of the critical analysis of modern approaches to treatment of a small intestine bacterial overgrowth syndrome (SIBO). SIBO now is one of the major problems in gastroenterology. At the same time, the bacterial overgrowth is cause and consequence of many diseases of digestive system and extradigestive manifestations. Many researches testify to prevalence of SIBO in patients with digestive diseases. However, pathogenesis of a disease is studied insufficiently today. Nevertheless, the available data of scientific researches allow to belong to the offered ways of diagnostics and treatment critically.Data on physiology of microbiota of the digestive tract of the healthy person are provided in a review. Mechanisms of antimicrobic resistance of a microbiota of intestines are considered. Interrelations between an antibiotikassociated degeneration of normal flora and bacterial overgrowth are presented. The analysis of an antibiotiktherapi of SIBO indicates low efficiency and also possible ways became chronicle diseaseand frequent recurrence of an illness. The multiple-factors and complexity of pathogenesis of SIBO are leaded authors to a conclusion to use ethiopathogenesis approaches for solution of SIBO.
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spelling doaj.art-91b5f833efea423a97c7566c8fd3c7462023-03-13T09:58:21ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842015-06-01143496210.20538/1682-0363-2015-3-49-62169THE ETHIOPATOGENESIS AND THE ANALYSIS OF AN ANTIBIOTIC TREATMENT OF A SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROMEV. L. Martynov0A. Kh. Khairdinov1Городская клиническая больница № 12, Нижний НовгородГородская клиническая больница № 12, Нижний НовгородArticle is attempt of the critical analysis of modern approaches to treatment of a small intestine bacterial overgrowth syndrome (SIBO). SIBO now is one of the major problems in gastroenterology. At the same time, the bacterial overgrowth is cause and consequence of many diseases of digestive system and extradigestive manifestations. Many researches testify to prevalence of SIBO in patients with digestive diseases. However, pathogenesis of a disease is studied insufficiently today. Nevertheless, the available data of scientific researches allow to belong to the offered ways of diagnostics and treatment critically.Data on physiology of microbiota of the digestive tract of the healthy person are provided in a review. Mechanisms of antimicrobic resistance of a microbiota of intestines are considered. Interrelations between an antibiotikassociated degeneration of normal flora and bacterial overgrowth are presented. The analysis of an antibiotiktherapi of SIBO indicates low efficiency and also possible ways became chronicle diseaseand frequent recurrence of an illness. The multiple-factors and complexity of pathogenesis of SIBO are leaded authors to a conclusion to use ethiopathogenesis approaches for solution of SIBO.https://bulletin.ssmu.ru/jour/article/view/171синдром избыточного бактериального ростаантибиотикотерапиярифаксимин
spellingShingle V. L. Martynov
A. Kh. Khairdinov
THE ETHIOPATOGENESIS AND THE ANALYSIS OF AN ANTIBIOTIC TREATMENT OF A SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROME
Бюллетень сибирской медицины
синдром избыточного бактериального роста
антибиотикотерапия
рифаксимин
title THE ETHIOPATOGENESIS AND THE ANALYSIS OF AN ANTIBIOTIC TREATMENT OF A SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROME
title_full THE ETHIOPATOGENESIS AND THE ANALYSIS OF AN ANTIBIOTIC TREATMENT OF A SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROME
title_fullStr THE ETHIOPATOGENESIS AND THE ANALYSIS OF AN ANTIBIOTIC TREATMENT OF A SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROME
title_full_unstemmed THE ETHIOPATOGENESIS AND THE ANALYSIS OF AN ANTIBIOTIC TREATMENT OF A SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROME
title_short THE ETHIOPATOGENESIS AND THE ANALYSIS OF AN ANTIBIOTIC TREATMENT OF A SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROME
title_sort ethiopatogenesis and the analysis of an antibiotic treatment of a small intestine bacterial overgrowth syndrome
topic синдром избыточного бактериального роста
антибиотикотерапия
рифаксимин
url https://bulletin.ssmu.ru/jour/article/view/171
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AT vlmartynov ethiopatogenesisandtheanalysisofanantibiotictreatmentofasmallintestinebacterialovergrowthsyndrome
AT akhkhairdinov ethiopatogenesisandtheanalysisofanantibiotictreatmentofasmallintestinebacterialovergrowthsyndrome