Vehicle-induced multiple trauma: Serum lactate level and prognosis

Background and Objectives: Early assessment of the severity and prognosis of multiple trauma injuries is crucial for the improvement of prognosis. Therefore, defining the parameters related to mortality and severity of multiple trauma injuries needs to be considered. The current study aims to invest...

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Main Authors: Shima Tayebi, Abolghasem Lali, Ali Asghar Darzi, Soraya Khafri, Shayan Alijanpour
Format: Article
Language:English
Published: Kashan University of Medical Sciences 2022-01-01
Series:Archives of Trauma Research
Subjects:
Online Access:http://www.archtrauma.com/article.asp?issn=2251-953X;year=2022;volume=11;issue=4;spage=165;epage=170;aulast=Tayebi
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author Shima Tayebi
Abolghasem Lali
Ali Asghar Darzi
Soraya Khafri
Shayan Alijanpour
author_facet Shima Tayebi
Abolghasem Lali
Ali Asghar Darzi
Soraya Khafri
Shayan Alijanpour
author_sort Shima Tayebi
collection DOAJ
description Background and Objectives: Early assessment of the severity and prognosis of multiple trauma injuries is crucial for the improvement of prognosis. Therefore, defining the parameters related to mortality and severity of multiple trauma injuries needs to be considered. The current study aims to investigate the serum lactate level and prognosis of these patients. Materials and Methods: This is a cross-sectional study conducted on 150 motor-vehicle-induced multiple trauma patients who were admitted to the Babol Trauma Center for 15 months. The serum lactate level was measured at the time of admission, 24 h, and 72 h after admission. The outcome of the patients was evaluated as death, hospitalization, or discharge. Results: Overall, 150 motor vehicle-induced trauma patients were enrolled in the study. Hyperlactatemia was seen in 33 (22%) patients in 24 h and 78 (52%) patients in 72 h after admission (P < 0.001). There was a clinically significant correlation between lactate level at the time of admission and the outcome of the patients (5.22 ± 3.41 expired, 2.69 ± 1.67 hospitalized, and 1.83 ± 1.09 discharged, P < 0.00). There was a clinically significant correlation between the serum lactate level at 24 h after admission and the outcome of the patients (6.81 ± 3.51 expired, 1.35 ± 0.79 hospitalized, and 0.83 ± 0.23 discharged, P < 0.001). There was also a clinically significant correlation between the outcome of the patients (discharge or hospitalization, or death) and the serum lactate level at the time of the admission and 24 h after the admission (P = 0.035). Conclusions: The baseline lactate, the lactate level at 24 h after admission, and the difference between these two can be used as a prognostic factor in the evaluation of multiple trauma patients. It is suggested to check the difference between the serum lactate level at the time of admission and 24 h later in trauma centers.
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spelling doaj.art-91ba6d4eacbf42a3b90928948fe0f3242023-09-03T14:29:09ZengKashan University of Medical SciencesArchives of Trauma Research2251-953X2251-95992022-01-0111416517010.4103/atr.atr_74_21Vehicle-induced multiple trauma: Serum lactate level and prognosisShima TayebiAbolghasem LaliAli Asghar DarziSoraya KhafriShayan AlijanpourBackground and Objectives: Early assessment of the severity and prognosis of multiple trauma injuries is crucial for the improvement of prognosis. Therefore, defining the parameters related to mortality and severity of multiple trauma injuries needs to be considered. The current study aims to investigate the serum lactate level and prognosis of these patients. Materials and Methods: This is a cross-sectional study conducted on 150 motor-vehicle-induced multiple trauma patients who were admitted to the Babol Trauma Center for 15 months. The serum lactate level was measured at the time of admission, 24 h, and 72 h after admission. The outcome of the patients was evaluated as death, hospitalization, or discharge. Results: Overall, 150 motor vehicle-induced trauma patients were enrolled in the study. Hyperlactatemia was seen in 33 (22%) patients in 24 h and 78 (52%) patients in 72 h after admission (P < 0.001). There was a clinically significant correlation between lactate level at the time of admission and the outcome of the patients (5.22 ± 3.41 expired, 2.69 ± 1.67 hospitalized, and 1.83 ± 1.09 discharged, P < 0.00). There was a clinically significant correlation between the serum lactate level at 24 h after admission and the outcome of the patients (6.81 ± 3.51 expired, 1.35 ± 0.79 hospitalized, and 0.83 ± 0.23 discharged, P < 0.001). There was also a clinically significant correlation between the outcome of the patients (discharge or hospitalization, or death) and the serum lactate level at the time of the admission and 24 h after the admission (P = 0.035). Conclusions: The baseline lactate, the lactate level at 24 h after admission, and the difference between these two can be used as a prognostic factor in the evaluation of multiple trauma patients. It is suggested to check the difference between the serum lactate level at the time of admission and 24 h later in trauma centers.http://www.archtrauma.com/article.asp?issn=2251-953X;year=2022;volume=11;issue=4;spage=165;epage=170;aulast=Tayebiiranlactic acidmultiple traumaprognosis
spellingShingle Shima Tayebi
Abolghasem Lali
Ali Asghar Darzi
Soraya Khafri
Shayan Alijanpour
Vehicle-induced multiple trauma: Serum lactate level and prognosis
Archives of Trauma Research
iran
lactic acid
multiple trauma
prognosis
title Vehicle-induced multiple trauma: Serum lactate level and prognosis
title_full Vehicle-induced multiple trauma: Serum lactate level and prognosis
title_fullStr Vehicle-induced multiple trauma: Serum lactate level and prognosis
title_full_unstemmed Vehicle-induced multiple trauma: Serum lactate level and prognosis
title_short Vehicle-induced multiple trauma: Serum lactate level and prognosis
title_sort vehicle induced multiple trauma serum lactate level and prognosis
topic iran
lactic acid
multiple trauma
prognosis
url http://www.archtrauma.com/article.asp?issn=2251-953X;year=2022;volume=11;issue=4;spage=165;epage=170;aulast=Tayebi
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AT aliasghardarzi vehicleinducedmultipletraumaserumlactatelevelandprognosis
AT sorayakhafri vehicleinducedmultipletraumaserumlactatelevelandprognosis
AT shayanalijanpour vehicleinducedmultipletraumaserumlactatelevelandprognosis