Anti-allergic activity of Thai medicinal plants used in longevity formulation
The ethanolic (EtOH) and water extracts of six plants including Piper nigrum, Streblus asper, Cyperus rotundus, Tinospora crispa, Diospyros rhodocalyx and Albizia procera used in Thai traditional longevity formulation, were examined for anti-allergic activity on antigen-induced b-hexosaminidase rele...
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| Format: | Article |
| Language: | English |
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Prince of Songkla University
2008-07-01
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| Series: | Songklanakarin Journal of Science and Technology (SJST) |
| Subjects: | |
| Online Access: | http://rdo.psu.ac.th/sjst/ejournal/journal/30-5/0125-3395-30-5-621-625.pdf |
| _version_ | 1811343703077289984 |
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| author | Sawanee Kraithep Kwunchit Oungbho Supinya Tewtrakul |
| author_facet | Sawanee Kraithep Kwunchit Oungbho Supinya Tewtrakul |
| author_sort | Sawanee Kraithep |
| collection | DOAJ |
| description | The ethanolic (EtOH) and water extracts of six plants including Piper nigrum, Streblus asper, Cyperus rotundus, Tinospora crispa, Diospyros rhodocalyx and Albizia procera used in Thai traditional longevity formulation, were examined for anti-allergic activity on antigen-induced b-hexosaminidase release from RBL-2H3 cells (rat-basophilic leukemia cell line), a tumor analog of mast cell. It was revealed that Piper nigrum (EtOH) extract exhibited the most potent activity with an IC<sub>50</sub> value of 14.0 μg/ml, which was higher than that of ketotifen fumarate, a positive control IC<sub>50</sub> = 20.2 μg/ml). It was also found that the preparations of Piper-Diospyros (EtOH) and Piper-Tinospora (EtOH) in the ratio of 1 : 1 appreciably inhibited antigen-induced degranulation in RBL-2H3 cells with IC<sub>50</sub> values of 23.5 and 26.7 μg/ml, respectively. The antiallergic effects of these two preparations were higher than that of the original longevity formulation (IC<sub>50</sub> = 66.6 μg/ml). |
| first_indexed | 2024-04-13T19:33:29Z |
| format | Article |
| id | doaj.art-91bc7fbfb52841bd8d1b787bedc06891 |
| institution | Directory Open Access Journal |
| issn | 0125-3395 |
| language | English |
| last_indexed | 2024-04-13T19:33:29Z |
| publishDate | 2008-07-01 |
| publisher | Prince of Songkla University |
| record_format | Article |
| series | Songklanakarin Journal of Science and Technology (SJST) |
| spelling | doaj.art-91bc7fbfb52841bd8d1b787bedc068912022-12-22T02:33:06ZengPrince of Songkla UniversitySongklanakarin Journal of Science and Technology (SJST)0125-33952008-07-01305621625Anti-allergic activity of Thai medicinal plants used in longevity formulationSawanee KraithepKwunchit OungbhoSupinya TewtrakulThe ethanolic (EtOH) and water extracts of six plants including Piper nigrum, Streblus asper, Cyperus rotundus, Tinospora crispa, Diospyros rhodocalyx and Albizia procera used in Thai traditional longevity formulation, were examined for anti-allergic activity on antigen-induced b-hexosaminidase release from RBL-2H3 cells (rat-basophilic leukemia cell line), a tumor analog of mast cell. It was revealed that Piper nigrum (EtOH) extract exhibited the most potent activity with an IC<sub>50</sub> value of 14.0 μg/ml, which was higher than that of ketotifen fumarate, a positive control IC<sub>50</sub> = 20.2 μg/ml). It was also found that the preparations of Piper-Diospyros (EtOH) and Piper-Tinospora (EtOH) in the ratio of 1 : 1 appreciably inhibited antigen-induced degranulation in RBL-2H3 cells with IC<sub>50</sub> values of 23.5 and 26.7 μg/ml, respectively. The antiallergic effects of these two preparations were higher than that of the original longevity formulation (IC<sub>50</sub> = 66.6 μg/ml).http://rdo.psu.ac.th/sjst/ejournal/journal/30-5/0125-3395-30-5-621-625.pdfThai longevity herbal formulationanti-allergic activityRBL-2H3 cells |
| spellingShingle | Sawanee Kraithep Kwunchit Oungbho Supinya Tewtrakul Anti-allergic activity of Thai medicinal plants used in longevity formulation Songklanakarin Journal of Science and Technology (SJST) Thai longevity herbal formulation anti-allergic activity RBL-2H3 cells |
| title | Anti-allergic activity of Thai medicinal plants used in longevity formulation |
| title_full | Anti-allergic activity of Thai medicinal plants used in longevity formulation |
| title_fullStr | Anti-allergic activity of Thai medicinal plants used in longevity formulation |
| title_full_unstemmed | Anti-allergic activity of Thai medicinal plants used in longevity formulation |
| title_short | Anti-allergic activity of Thai medicinal plants used in longevity formulation |
| title_sort | anti allergic activity of thai medicinal plants used in longevity formulation |
| topic | Thai longevity herbal formulation anti-allergic activity RBL-2H3 cells |
| url | http://rdo.psu.ac.th/sjst/ejournal/journal/30-5/0125-3395-30-5-621-625.pdf |
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