A randomized clinical trial on treatment of chronic constipation by traditional persian medicine recommendations compared to allopathic medicine: A pilot study
Background: The aim of this study was to compare the efficacy and side effects of lactulose plus traditional Persian medicine with only lactulose on the functional chronic constipation. Methods: Participants included 20 patients (10 in each group) aged 18–80 years, with major inclusion criteria of R...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | International Journal of Preventive Medicine |
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| Online Access: | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2017;volume=8;issue=1;spage=50;epage=50;aulast= |
| _version_ | 1818581500563554304 |
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| author | Mohammad Reza Fattahi Seyed Morteza Emami Alorizi Majid Nimrouzi Mohammad M Zarshenas Mohammad Mahdi Parvizi |
| author_facet | Mohammad Reza Fattahi Seyed Morteza Emami Alorizi Majid Nimrouzi Mohammad M Zarshenas Mohammad Mahdi Parvizi |
| author_sort | Mohammad Reza Fattahi |
| collection | DOAJ |
| description | Background: The aim of this study was to compare the efficacy and side effects of lactulose plus traditional Persian medicine with only lactulose on the functional chronic constipation. Methods: Participants included 20 patients (10 in each group) aged 18–80 years, with major inclusion criteria of ROME III. They were assigned into two parallel therapeutic groups, including the intervention group (lactulose plus traditional Persian medicine [TPM] advices) and control group (only lactulose) through a block randomization. Weekly follow-up was done for 1 month for both groups. Results: After the intervention, the frequency of bowel habit increased significantly in patients of both groups (P = 0.001), and the frequency of hard stool defecation, sensation of painful defecation, sensation of incomplete evacuation, sensation of anorectal obstruction, and manual maneuver for evacuation were decreased significantly in patients of both groups (P < 0.001 for all comparisons and 0.025 for manual maneuver). However, the only significant difference between the two groups was more reduction in the sensation of painful defecation in the lactulose group versus lactulose plus TPM advices (P = 0.014). Conclusions: Based on the pilot study, no significant difference was shown between TPM with lactulose and lactulose only in the management of chronic functional constipation. However, the easy recommendations of TPM can be useful in improving chronic constipation. |
| first_indexed | 2024-12-16T07:34:29Z |
| format | Article |
| id | doaj.art-91be33b3bd244379abbc534095913ef8 |
| institution | Directory Open Access Journal |
| issn | 2008-7802 2008-8213 |
| language | English |
| last_indexed | 2024-12-16T07:34:29Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Preventive Medicine |
| spelling | doaj.art-91be33b3bd244379abbc534095913ef82022-12-21T22:39:16ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132017-01-0181505010.4103/ijpvm.IJPVM_302_16A randomized clinical trial on treatment of chronic constipation by traditional persian medicine recommendations compared to allopathic medicine: A pilot studyMohammad Reza FattahiSeyed Morteza Emami AloriziMajid NimrouziMohammad M ZarshenasMohammad Mahdi ParviziBackground: The aim of this study was to compare the efficacy and side effects of lactulose plus traditional Persian medicine with only lactulose on the functional chronic constipation. Methods: Participants included 20 patients (10 in each group) aged 18–80 years, with major inclusion criteria of ROME III. They were assigned into two parallel therapeutic groups, including the intervention group (lactulose plus traditional Persian medicine [TPM] advices) and control group (only lactulose) through a block randomization. Weekly follow-up was done for 1 month for both groups. Results: After the intervention, the frequency of bowel habit increased significantly in patients of both groups (P = 0.001), and the frequency of hard stool defecation, sensation of painful defecation, sensation of incomplete evacuation, sensation of anorectal obstruction, and manual maneuver for evacuation were decreased significantly in patients of both groups (P < 0.001 for all comparisons and 0.025 for manual maneuver). However, the only significant difference between the two groups was more reduction in the sensation of painful defecation in the lactulose group versus lactulose plus TPM advices (P = 0.014). Conclusions: Based on the pilot study, no significant difference was shown between TPM with lactulose and lactulose only in the management of chronic functional constipation. However, the easy recommendations of TPM can be useful in improving chronic constipation.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2017;volume=8;issue=1;spage=50;epage=50;aulast=Chronic functional constipationlactulosetraditional Persian medicine |
| spellingShingle | Mohammad Reza Fattahi Seyed Morteza Emami Alorizi Majid Nimrouzi Mohammad M Zarshenas Mohammad Mahdi Parvizi A randomized clinical trial on treatment of chronic constipation by traditional persian medicine recommendations compared to allopathic medicine: A pilot study International Journal of Preventive Medicine Chronic functional constipation lactulose traditional Persian medicine |
| title | A randomized clinical trial on treatment of chronic constipation by traditional persian medicine recommendations compared to allopathic medicine: A pilot study |
| title_full | A randomized clinical trial on treatment of chronic constipation by traditional persian medicine recommendations compared to allopathic medicine: A pilot study |
| title_fullStr | A randomized clinical trial on treatment of chronic constipation by traditional persian medicine recommendations compared to allopathic medicine: A pilot study |
| title_full_unstemmed | A randomized clinical trial on treatment of chronic constipation by traditional persian medicine recommendations compared to allopathic medicine: A pilot study |
| title_short | A randomized clinical trial on treatment of chronic constipation by traditional persian medicine recommendations compared to allopathic medicine: A pilot study |
| title_sort | randomized clinical trial on treatment of chronic constipation by traditional persian medicine recommendations compared to allopathic medicine a pilot study |
| topic | Chronic functional constipation lactulose traditional Persian medicine |
| url | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2017;volume=8;issue=1;spage=50;epage=50;aulast= |
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