A Case of Paraneoplastic Demyelinating Motor Polyneuropathy
Peripheral neuropathy is commonly accompanied by cancer but demyelinating ones are not commonly reported. We report the clinical, neurophysiological, and biological characteristics of an 82-year-old patient who presented with a demyelinating motor neuropathy and high titre of anti-ganglioside antibo...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2012-04-01
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| Series: | Case Reports in Neurology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/338296 |
| _version_ | 1818903110412664832 |
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| author | Sohrab Mostoufizadeh Maryam Souri Jérôme de Seze |
| author_facet | Sohrab Mostoufizadeh Maryam Souri Jérôme de Seze |
| author_sort | Sohrab Mostoufizadeh |
| collection | DOAJ |
| description | Peripheral neuropathy is commonly accompanied by cancer but demyelinating ones are not commonly reported. We report the clinical, neurophysiological, and biological characteristics of an 82-year-old patient who presented with a demyelinating motor neuropathy and high titre of anti-ganglioside antibodies associated with oesophageal cancer. The neurological course worsened rapidly despite immunotherapy, leading to a bedridden status. We propose to suspect a paraneoplastic origin in older patients or when the clinical course progresses rapidly within a few weeks or months. |
| first_indexed | 2024-12-19T20:46:20Z |
| format | Article |
| id | doaj.art-91c396b914bc4c9d91615241a1ad8067 |
| institution | Directory Open Access Journal |
| issn | 1662-680X |
| language | English |
| last_indexed | 2024-12-19T20:46:20Z |
| publishDate | 2012-04-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Neurology |
| spelling | doaj.art-91c396b914bc4c9d91615241a1ad80672022-12-21T20:06:14ZengKarger PublishersCase Reports in Neurology1662-680X2012-04-0141717610.1159/000338296338296A Case of Paraneoplastic Demyelinating Motor PolyneuropathySohrab MostoufizadehMaryam SouriJérôme de SezePeripheral neuropathy is commonly accompanied by cancer but demyelinating ones are not commonly reported. We report the clinical, neurophysiological, and biological characteristics of an 82-year-old patient who presented with a demyelinating motor neuropathy and high titre of anti-ganglioside antibodies associated with oesophageal cancer. The neurological course worsened rapidly despite immunotherapy, leading to a bedridden status. We propose to suspect a paraneoplastic origin in older patients or when the clinical course progresses rapidly within a few weeks or months.http://www.karger.com/Article/FullText/338296Motor neuropathyConduction blockParaneoplastic neuropathyCancerOnconeural antibodiesAnti-ganglioside antibodies |
| spellingShingle | Sohrab Mostoufizadeh Maryam Souri Jérôme de Seze A Case of Paraneoplastic Demyelinating Motor Polyneuropathy Case Reports in Neurology Motor neuropathy Conduction block Paraneoplastic neuropathy Cancer Onconeural antibodies Anti-ganglioside antibodies |
| title | A Case of Paraneoplastic Demyelinating Motor Polyneuropathy |
| title_full | A Case of Paraneoplastic Demyelinating Motor Polyneuropathy |
| title_fullStr | A Case of Paraneoplastic Demyelinating Motor Polyneuropathy |
| title_full_unstemmed | A Case of Paraneoplastic Demyelinating Motor Polyneuropathy |
| title_short | A Case of Paraneoplastic Demyelinating Motor Polyneuropathy |
| title_sort | case of paraneoplastic demyelinating motor polyneuropathy |
| topic | Motor neuropathy Conduction block Paraneoplastic neuropathy Cancer Onconeural antibodies Anti-ganglioside antibodies |
| url | http://www.karger.com/Article/FullText/338296 |
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