Butamirate citrate associated methemoglobinemia
Methemoglobinemia is a potentially life-threatening disease resulting from high blood levels of methemoglobin resulting in failure of binding and delivery of oxygen to tissues. The most common causes of methemoglobinemia are oxidizing toxins, such as butamirate citrate, which is a commonly used liqu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Tungs’ Medical Journal |
| Subjects: | |
| Online Access: | https://journals.lww.com/TMJ/Pages/default.aspx/article.asp?issn=2071-3592;year=2023;volume=17;issue=2;spage=98;epage=101;aulast=Kao |
| _version_ | 1797302010683326464 |
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| author | Chung-Chih Kao Shu-Wei Hu Hueng-Chuen Fan |
| author_facet | Chung-Chih Kao Shu-Wei Hu Hueng-Chuen Fan |
| author_sort | Chung-Chih Kao |
| collection | DOAJ |
| description | Methemoglobinemia is a potentially life-threatening disease resulting from high blood levels of methemoglobin resulting in failure of binding and delivery of oxygen to tissues. The most common causes of methemoglobinemia are oxidizing toxins, such as butamirate citrate, which is a commonly used liquid antitussive, especially in pediatric patients. Herein, we present the case of a 3-year-old girl who accidentally ingested excessive amounts of butamirate citrate. She presented with mild lip cyanosis with high methemoglobin levels (6.5%) and normal oxygen saturation (98%), and was managed by prompt gut decontamination with activated charcoal, followed by monitoring and intravenous glucose administration. Therefore, methemoglobinemia should be considered a differential diagnosis in a patient presenting with cyanosis without any underlying lung or heart disease. |
| first_indexed | 2024-03-07T23:30:45Z |
| format | Article |
| id | doaj.art-91c4823636b64e37ab227d947447ac25 |
| institution | Directory Open Access Journal |
| issn | 2071-3592 |
| language | English |
| last_indexed | 2024-03-07T23:30:45Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Tungs’ Medical Journal |
| spelling | doaj.art-91c4823636b64e37ab227d947447ac252024-02-20T15:47:07ZengWolters Kluwer Medknow PublicationsTungs’ Medical Journal2071-35922023-01-011729810110.4103/ETMJ.ETMJ-D-23-00020Butamirate citrate associated methemoglobinemiaChung-Chih KaoShu-Wei HuHueng-Chuen FanMethemoglobinemia is a potentially life-threatening disease resulting from high blood levels of methemoglobin resulting in failure of binding and delivery of oxygen to tissues. The most common causes of methemoglobinemia are oxidizing toxins, such as butamirate citrate, which is a commonly used liquid antitussive, especially in pediatric patients. Herein, we present the case of a 3-year-old girl who accidentally ingested excessive amounts of butamirate citrate. She presented with mild lip cyanosis with high methemoglobin levels (6.5%) and normal oxygen saturation (98%), and was managed by prompt gut decontamination with activated charcoal, followed by monitoring and intravenous glucose administration. Therefore, methemoglobinemia should be considered a differential diagnosis in a patient presenting with cyanosis without any underlying lung or heart disease.https://journals.lww.com/TMJ/Pages/default.aspx/article.asp?issn=2071-3592;year=2023;volume=17;issue=2;spage=98;epage=101;aulast=Kaobutamirate citratehypoxemiamethemoglobin |
| spellingShingle | Chung-Chih Kao Shu-Wei Hu Hueng-Chuen Fan Butamirate citrate associated methemoglobinemia Tungs’ Medical Journal butamirate citrate hypoxemia methemoglobin |
| title | Butamirate citrate associated methemoglobinemia |
| title_full | Butamirate citrate associated methemoglobinemia |
| title_fullStr | Butamirate citrate associated methemoglobinemia |
| title_full_unstemmed | Butamirate citrate associated methemoglobinemia |
| title_short | Butamirate citrate associated methemoglobinemia |
| title_sort | butamirate citrate associated methemoglobinemia |
| topic | butamirate citrate hypoxemia methemoglobin |
| url | https://journals.lww.com/TMJ/Pages/default.aspx/article.asp?issn=2071-3592;year=2023;volume=17;issue=2;spage=98;epage=101;aulast=Kao |
| work_keys_str_mv | AT chungchihkao butamiratecitrateassociatedmethemoglobinemia AT shuweihu butamiratecitrateassociatedmethemoglobinemia AT huengchuenfan butamiratecitrateassociatedmethemoglobinemia |