The relationship between myocardial perfusion scanning results, C-reactive protein to albumin ratio, systemic inflammatory response index and coronary angiographic findings
<b>Aim:</b> We aimed to investigate whether C-reactive protein to albumin ratio (CAR) and systemic inflammatory response index (SIRI) have an additional value in interpretation of myocardial perfusion scanning (MPS) results.<br /> <b>Background:</b> MPS have high sensit...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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National Scientific Medical Center
2022-08-01
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| Series: | Ķazaķstannyṇ Klinikalyķ Medicinasy |
| Subjects: | |
| Online Access: | https://www.clinmedkaz.org/download/the-relationship-between-myocardial-perfusion-scanning-results-c-reactive-protein-to-albumin-ratio-12332.pdf |
| _version_ | 1797980232743911424 |
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| author | Yasin Yüksel Cennet Yıldız |
| author_facet | Yasin Yüksel Cennet Yıldız |
| author_sort | Yasin Yüksel |
| collection | DOAJ |
| description | <b>Aim:</b> We aimed to investigate whether C-reactive protein to albumin ratio (CAR) and systemic inflammatory response index (SIRI) have an additional value in interpretation of myocardial perfusion scanning (MPS) results.<br />
<b>Background:</b> MPS have high sensitivity but relatively low specificity in diagnosis of coronary artery disease (CAD).<br />
<b>Material and methods:</b> 449 patients who had MPS before coronary angiography were included. Patients with and without CAD constituted study (n=227) and control (n=222) groups, respectively.<br />
<b>Results:</b> Sensitivity and specificity of MPS in detecting CAD were found to be as 97.8% and 62.2%, respectively. CAR value of 1.22 and SIRI value of 1.45 predicted CAD with a sensitivity of 61.2% and 59% and specificity of 77% and 80.2%, respectively. Only 10.4 % of the CAD negative patients had positive MPS and positive CAR values, whereas 0.9% of the CAD positive patients had negative MPS and negative CAR values. 27.5% of CAD negative patients had positive MPS and negative CAR values. Likewise, having a negative MPS with negative SIRI value identified 50% of the patients who had normal coronary arteries. Positive MPS with positive SIRI value correctly identified 58.1% of patients who had CAD.<br />
<b>Conclusion:</b> evaluation of CAR and SIRI might be beneficial in interpretation of MPS. |
| first_indexed | 2024-04-11T05:51:16Z |
| format | Article |
| id | doaj.art-91c919f3bfad4b2594325197b87b7de6 |
| institution | Directory Open Access Journal |
| issn | 1812-2892 2313-1519 |
| language | English |
| last_indexed | 2024-04-11T05:51:16Z |
| publishDate | 2022-08-01 |
| publisher | National Scientific Medical Center |
| record_format | Article |
| series | Ķazaķstannyṇ Klinikalyķ Medicinasy |
| spelling | doaj.art-91c919f3bfad4b2594325197b87b7de62022-12-22T04:42:03ZengNational Scientific Medical CenterĶazaķstannyṇ Klinikalyķ Medicinasy1812-28922313-15192022-08-01194485210.23950/jcmk/12332The relationship between myocardial perfusion scanning results, C-reactive protein to albumin ratio, systemic inflammatory response index and coronary angiographic findingsYasin Yüksel0Cennet Yıldız1Department of Cardiology, Istanbul Education and Research Hospital, Istanbul, TurkeyDepartment of Cardiology, Bakırköy Dr Sadi Konuk Education and Research Hospital, Istanbul, Turkey<b>Aim:</b> We aimed to investigate whether C-reactive protein to albumin ratio (CAR) and systemic inflammatory response index (SIRI) have an additional value in interpretation of myocardial perfusion scanning (MPS) results.<br /> <b>Background:</b> MPS have high sensitivity but relatively low specificity in diagnosis of coronary artery disease (CAD).<br /> <b>Material and methods:</b> 449 patients who had MPS before coronary angiography were included. Patients with and without CAD constituted study (n=227) and control (n=222) groups, respectively.<br /> <b>Results:</b> Sensitivity and specificity of MPS in detecting CAD were found to be as 97.8% and 62.2%, respectively. CAR value of 1.22 and SIRI value of 1.45 predicted CAD with a sensitivity of 61.2% and 59% and specificity of 77% and 80.2%, respectively. Only 10.4 % of the CAD negative patients had positive MPS and positive CAR values, whereas 0.9% of the CAD positive patients had negative MPS and negative CAR values. 27.5% of CAD negative patients had positive MPS and negative CAR values. Likewise, having a negative MPS with negative SIRI value identified 50% of the patients who had normal coronary arteries. Positive MPS with positive SIRI value correctly identified 58.1% of patients who had CAD.<br /> <b>Conclusion:</b> evaluation of CAR and SIRI might be beneficial in interpretation of MPS.https://www.clinmedkaz.org/download/the-relationship-between-myocardial-perfusion-scanning-results-c-reactive-protein-to-albumin-ratio-12332.pdfinflammationbiomarkerscoronary artery diseasemyocardial perfusion scanning |
| spellingShingle | Yasin Yüksel Cennet Yıldız The relationship between myocardial perfusion scanning results, C-reactive protein to albumin ratio, systemic inflammatory response index and coronary angiographic findings Ķazaķstannyṇ Klinikalyķ Medicinasy inflammation biomarkers coronary artery disease myocardial perfusion scanning |
| title | The relationship between myocardial perfusion scanning results, C-reactive protein to albumin ratio, systemic inflammatory response index and coronary angiographic findings |
| title_full | The relationship between myocardial perfusion scanning results, C-reactive protein to albumin ratio, systemic inflammatory response index and coronary angiographic findings |
| title_fullStr | The relationship between myocardial perfusion scanning results, C-reactive protein to albumin ratio, systemic inflammatory response index and coronary angiographic findings |
| title_full_unstemmed | The relationship between myocardial perfusion scanning results, C-reactive protein to albumin ratio, systemic inflammatory response index and coronary angiographic findings |
| title_short | The relationship between myocardial perfusion scanning results, C-reactive protein to albumin ratio, systemic inflammatory response index and coronary angiographic findings |
| title_sort | relationship between myocardial perfusion scanning results c reactive protein to albumin ratio systemic inflammatory response index and coronary angiographic findings |
| topic | inflammation biomarkers coronary artery disease myocardial perfusion scanning |
| url | https://www.clinmedkaz.org/download/the-relationship-between-myocardial-perfusion-scanning-results-c-reactive-protein-to-albumin-ratio-12332.pdf |
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