Assessing the Quality of Life, Coping Strategies, Anxiety and Depression Levels in Patients with Long-COVID-19 Syndrome: A Six-Month Follow-Up Study

This longitudinal study investigates the psychosocial effects of long-COVID Syndrome, a domain still not extensively researched. It specifically evaluates the quality of life, coping mechanisms, anxiety and depression levels in COVID-19 survivors, differentiating between those with and without long-...

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Main Authors: Adrian Vasile Bota, Felix Bratosin, Iulia Bogdan, Susa Septimiu-Radu, Adrian Cosmin Ilie, Sonia-Roxana Burtic, David Vladut Razvan, Raluca Tudor, Mirela Florica Indries, Andrei Nicolae Csep, Ariadna Petronela Fildan, Camelia Melania Budea, Iosif Marincu
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Diseases
Subjects:
Online Access:https://www.mdpi.com/2079-9721/12/1/21
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author Adrian Vasile Bota
Felix Bratosin
Iulia Bogdan
Susa Septimiu-Radu
Adrian Cosmin Ilie
Sonia-Roxana Burtic
David Vladut Razvan
Raluca Tudor
Mirela Florica Indries
Andrei Nicolae Csep
Ariadna Petronela Fildan
Camelia Melania Budea
Iosif Marincu
author_facet Adrian Vasile Bota
Felix Bratosin
Iulia Bogdan
Susa Septimiu-Radu
Adrian Cosmin Ilie
Sonia-Roxana Burtic
David Vladut Razvan
Raluca Tudor
Mirela Florica Indries
Andrei Nicolae Csep
Ariadna Petronela Fildan
Camelia Melania Budea
Iosif Marincu
author_sort Adrian Vasile Bota
collection DOAJ
description This longitudinal study investigates the psychosocial effects of long-COVID Syndrome, a domain still not extensively researched. It specifically evaluates the quality of life, coping mechanisms, anxiety and depression levels in COVID-19 survivors, differentiating between those with and without long-COVID Syndrome. Conducted at the Victor Babes Hospital for Infectious Diseases and Pulmonology in Timisoara, Romania, the study utilized a cohort of patients diagnosed with mild to moderate COVID-19. The following standardized tools: WHOQOL-BREF for quality of life, COPE-60 for coping strategies, and the Hospital Anxiety and Depression Scale (HADS), were employed for the assessment. The sample consisted of 86 patients displaying persistent post-acute symptoms and 432 asymptomatic patients at the 6-month post-discharge mark. Patients with frequent post-acute symptoms reported significantly higher levels of fatigue (8.2 ± 1.4), cognitive difficulties (7.5 ± 1.6), and respiratory challenges (7.8 ± 1.3), along with a markedly lower overall quality of life (7.0 ± 1.5) compared to their asymptomatic counterparts. HADS scores revealed elevated depression (6.8 ± 1.9) and anxiety (7.1 ± 2.3) in the symptomatic group. Quality of life, as evaluated through the use of WHOQOL-BREF, showed lower scores in the symptomatic cohort across physical (58.8 ± 15.8), mental (56.3 ± 16.4), and social domains (50.2 ± 17.5). COPE-60 findings indicated a higher prevalence of disengagement (56.4%) and emotion-focused coping strategies (61.8%) in the symptomatic group, in contrast to 30.1% and 37.0%, respectively, in the asymptomatic group. The study highlights that long-COVID Syndrome significantly deteriorates the quality of life and is associated with increased depression and anxiety levels. The prevalent use of disengagement and emotion-focused coping strategies among patients with persistent symptoms suggests a need for enhanced psychosocial support tailored to this subgroup.
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spelling doaj.art-91ca28db62fb4faa8c1a1300f187cf602024-01-26T16:03:42ZengMDPI AGDiseases2079-97212024-01-011212110.3390/diseases12010021Assessing the Quality of Life, Coping Strategies, Anxiety and Depression Levels in Patients with Long-COVID-19 Syndrome: A Six-Month Follow-Up StudyAdrian Vasile Bota0Felix Bratosin1Iulia Bogdan2Susa Septimiu-Radu3Adrian Cosmin Ilie4Sonia-Roxana Burtic5David Vladut Razvan6Raluca Tudor7Mirela Florica Indries8Andrei Nicolae Csep9Ariadna Petronela Fildan10Camelia Melania Budea11Iosif Marincu12Methodological and Infectious Diseases Research Center, Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaMethodological and Infectious Diseases Research Center, Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaMethodological and Infectious Diseases Research Center, Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaMethodological and Infectious Diseases Research Center, Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaDepartment III Functional Sciences, Division of Public Health and Management, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaDoctoral School, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaMethodological and Infectious Diseases Research Center, Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaSecond Discipline of Neurology, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaDepartment of Psycho-Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, Str. Universitatii nr. 1, 410087 Oradea, RomaniaDepartment of Psycho-Neuroscience and Recovery, Faculty of Medicine and Pharmacy, University of Oradea, Str. Universitatii nr. 1, 410087 Oradea, RomaniaDepartment of Pulmonology, Faculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, RomaniaMethodological and Infectious Diseases Research Center, Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaMethodological and Infectious Diseases Research Center, Department of Infectious Diseases, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaThis longitudinal study investigates the psychosocial effects of long-COVID Syndrome, a domain still not extensively researched. It specifically evaluates the quality of life, coping mechanisms, anxiety and depression levels in COVID-19 survivors, differentiating between those with and without long-COVID Syndrome. Conducted at the Victor Babes Hospital for Infectious Diseases and Pulmonology in Timisoara, Romania, the study utilized a cohort of patients diagnosed with mild to moderate COVID-19. The following standardized tools: WHOQOL-BREF for quality of life, COPE-60 for coping strategies, and the Hospital Anxiety and Depression Scale (HADS), were employed for the assessment. The sample consisted of 86 patients displaying persistent post-acute symptoms and 432 asymptomatic patients at the 6-month post-discharge mark. Patients with frequent post-acute symptoms reported significantly higher levels of fatigue (8.2 ± 1.4), cognitive difficulties (7.5 ± 1.6), and respiratory challenges (7.8 ± 1.3), along with a markedly lower overall quality of life (7.0 ± 1.5) compared to their asymptomatic counterparts. HADS scores revealed elevated depression (6.8 ± 1.9) and anxiety (7.1 ± 2.3) in the symptomatic group. Quality of life, as evaluated through the use of WHOQOL-BREF, showed lower scores in the symptomatic cohort across physical (58.8 ± 15.8), mental (56.3 ± 16.4), and social domains (50.2 ± 17.5). COPE-60 findings indicated a higher prevalence of disengagement (56.4%) and emotion-focused coping strategies (61.8%) in the symptomatic group, in contrast to 30.1% and 37.0%, respectively, in the asymptomatic group. The study highlights that long-COVID Syndrome significantly deteriorates the quality of life and is associated with increased depression and anxiety levels. The prevalent use of disengagement and emotion-focused coping strategies among patients with persistent symptoms suggests a need for enhanced psychosocial support tailored to this subgroup.https://www.mdpi.com/2079-9721/12/1/21COVID-19post-acute COVIDlong COVID
spellingShingle Adrian Vasile Bota
Felix Bratosin
Iulia Bogdan
Susa Septimiu-Radu
Adrian Cosmin Ilie
Sonia-Roxana Burtic
David Vladut Razvan
Raluca Tudor
Mirela Florica Indries
Andrei Nicolae Csep
Ariadna Petronela Fildan
Camelia Melania Budea
Iosif Marincu
Assessing the Quality of Life, Coping Strategies, Anxiety and Depression Levels in Patients with Long-COVID-19 Syndrome: A Six-Month Follow-Up Study
Diseases
COVID-19
post-acute COVID
long COVID
title Assessing the Quality of Life, Coping Strategies, Anxiety and Depression Levels in Patients with Long-COVID-19 Syndrome: A Six-Month Follow-Up Study
title_full Assessing the Quality of Life, Coping Strategies, Anxiety and Depression Levels in Patients with Long-COVID-19 Syndrome: A Six-Month Follow-Up Study
title_fullStr Assessing the Quality of Life, Coping Strategies, Anxiety and Depression Levels in Patients with Long-COVID-19 Syndrome: A Six-Month Follow-Up Study
title_full_unstemmed Assessing the Quality of Life, Coping Strategies, Anxiety and Depression Levels in Patients with Long-COVID-19 Syndrome: A Six-Month Follow-Up Study
title_short Assessing the Quality of Life, Coping Strategies, Anxiety and Depression Levels in Patients with Long-COVID-19 Syndrome: A Six-Month Follow-Up Study
title_sort assessing the quality of life coping strategies anxiety and depression levels in patients with long covid 19 syndrome a six month follow up study
topic COVID-19
post-acute COVID
long COVID
url https://www.mdpi.com/2079-9721/12/1/21
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