PENGARUH APLIKASI VIRGIN COCONUT OIL TERHADAP PENINGKATAN JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI PADA RATTUS NOVERGICUS
Background: Wound healing is a complex biological process. Fibroblast is one of cell which is responsible for the wound healing process. Virgin Coconut Oil (VCO) have health benefit as antibacterial, antiinflamatory, antioxidant, and immunomodulatory. This research was purposed to know the influence...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Universitas Islam Sultan Agung
2015-12-01
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| Series: | ODONTO: Dental Journal |
| Online Access: | http://jurnal.unissula.ac.id/index.php/odj/article/view/280 |
| _version_ | 1819117933786300416 |
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| author | Anggun Hibah Jannah Tamara Yayun Siti Rochmah Rochman Mujayanto |
| author_facet | Anggun Hibah Jannah Tamara Yayun Siti Rochmah Rochman Mujayanto |
| author_sort | Anggun Hibah Jannah Tamara |
| collection | DOAJ |
| description | Background: Wound healing is a complex biological process. Fibroblast is one of cell which is responsible for the wound healing process. Virgin Coconut Oil (VCO) have health benefit as antibacterial, antiinflamatory, antioxidant, and immunomodulatory. This research was purposed to know the influence use of VCO over the amount of fibroblast in wound healing after dental extraction.Method: Research quasi experimental with post test control group design and using 15 Rattus novergicus which were divided into three groups (control positive, VCO topical application, and VCO per oral application). Tooth removal was committed by using explorer, scalpel-blade, and arterial clamp. Then VCO applied everyday for 7 days. Day 7th Rattus novergicus were died, the socket after extraction were made into histological form, then the amount of fibroblast were counted with 5 field of views and made in average. Result: The number of fibroblast of the most numerous was VCO per oral ( 48,6 ± 49,8 ), VCO topical ( 36,2 ± 38,8 ), and control positive ( 33,4 ± 35,2 ). The results of the Saphiro Wilk test and Levene test acquired data normally distributed and homogeny, so it continued to One Way Anova and data showed there were significant difference among the groups of samples with value p<0,05.Conclusion: The conclusion of this research is VCO could increase the number of fibroblasts in wound healing after dental extractions
Keywords: Tooth extraction, Virgin Coconut Oil, Fibroblast. |
| first_indexed | 2024-12-22T05:40:51Z |
| format | Article |
| id | doaj.art-91ca4c92af004c93957d4c606e6532da |
| institution | Directory Open Access Journal |
| issn | 2354-5992 2460-4119 |
| language | English |
| last_indexed | 2024-12-22T05:40:51Z |
| publishDate | 2015-12-01 |
| publisher | Universitas Islam Sultan Agung |
| record_format | Article |
| series | ODONTO: Dental Journal |
| spelling | doaj.art-91ca4c92af004c93957d4c606e6532da2022-12-21T18:37:11ZengUniversitas Islam Sultan AgungODONTO: Dental Journal2354-59922460-41192015-12-0112293410.30659/odj.1.2.29-34277PENGARUH APLIKASI VIRGIN COCONUT OIL TERHADAP PENINGKATAN JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI PADA RATTUS NOVERGICUSAnggun Hibah Jannah TamaraYayun Siti RochmahRochman MujayantoBackground: Wound healing is a complex biological process. Fibroblast is one of cell which is responsible for the wound healing process. Virgin Coconut Oil (VCO) have health benefit as antibacterial, antiinflamatory, antioxidant, and immunomodulatory. This research was purposed to know the influence use of VCO over the amount of fibroblast in wound healing after dental extraction.Method: Research quasi experimental with post test control group design and using 15 Rattus novergicus which were divided into three groups (control positive, VCO topical application, and VCO per oral application). Tooth removal was committed by using explorer, scalpel-blade, and arterial clamp. Then VCO applied everyday for 7 days. Day 7th Rattus novergicus were died, the socket after extraction were made into histological form, then the amount of fibroblast were counted with 5 field of views and made in average. Result: The number of fibroblast of the most numerous was VCO per oral ( 48,6 ± 49,8 ), VCO topical ( 36,2 ± 38,8 ), and control positive ( 33,4 ± 35,2 ). The results of the Saphiro Wilk test and Levene test acquired data normally distributed and homogeny, so it continued to One Way Anova and data showed there were significant difference among the groups of samples with value p<0,05.Conclusion: The conclusion of this research is VCO could increase the number of fibroblasts in wound healing after dental extractions Keywords: Tooth extraction, Virgin Coconut Oil, Fibroblast.http://jurnal.unissula.ac.id/index.php/odj/article/view/280 |
| spellingShingle | Anggun Hibah Jannah Tamara Yayun Siti Rochmah Rochman Mujayanto PENGARUH APLIKASI VIRGIN COCONUT OIL TERHADAP PENINGKATAN JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI PADA RATTUS NOVERGICUS ODONTO: Dental Journal |
| title | PENGARUH APLIKASI VIRGIN COCONUT OIL TERHADAP PENINGKATAN JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI PADA RATTUS NOVERGICUS |
| title_full | PENGARUH APLIKASI VIRGIN COCONUT OIL TERHADAP PENINGKATAN JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI PADA RATTUS NOVERGICUS |
| title_fullStr | PENGARUH APLIKASI VIRGIN COCONUT OIL TERHADAP PENINGKATAN JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI PADA RATTUS NOVERGICUS |
| title_full_unstemmed | PENGARUH APLIKASI VIRGIN COCONUT OIL TERHADAP PENINGKATAN JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI PADA RATTUS NOVERGICUS |
| title_short | PENGARUH APLIKASI VIRGIN COCONUT OIL TERHADAP PENINGKATAN JUMLAH FIBROBLAS PADA LUKA PASCA PENCABUTAN GIGI PADA RATTUS NOVERGICUS |
| title_sort | pengaruh aplikasi virgin coconut oil terhadap peningkatan jumlah fibroblas pada luka pasca pencabutan gigi pada rattus novergicus |
| url | http://jurnal.unissula.ac.id/index.php/odj/article/view/280 |
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