Hemodynamic Effect of 2% Lidocaine with 1:80,000 Epinephrine Infiltration in Maxillofacial Surgeries under General Anesthesia
Introduction: Epinephrine-containing lidocaine is the most used anestheic drug in dentistry. The aim of this study was to investigate the hemodynamic changes following local infiltration of 2%lidocaine with 1:80,000 epinephrine in subjects undergoing orthognatic surgery under general anesthesia. Met...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2013-01-01
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| Series: | Journal of Dental Materials and Techniques |
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| Online Access: | http://jdmt.mums.ac.ir/pdf_147_ae0fbd97cceec354d712aa5e7c082686.html |
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| author | Baratollah Shaban Elham Moradi Amir Hossein Nejat Somayeh Sabzali Zanjanhkhah Touraj Vaezi |
| author_facet | Baratollah Shaban Elham Moradi Amir Hossein Nejat Somayeh Sabzali Zanjanhkhah Touraj Vaezi |
| author_sort | Baratollah Shaban |
| collection | DOAJ |
| description | Introduction: Epinephrine-containing lidocaine is the most used anestheic drug in dentistry. The aim of this study was to investigate the hemodynamic changes following local infiltration of 2%lidocaine with 1:80,000 epinephrine in subjects undergoing orthognatic surgery under general anesthesia. Methods: Twenty five patients without any systemic disease participated. After general anesthesia, two cartridges of 2% lidocaine + 1:80,000 epinephrine were infiltrated around the surgery site. Systolic (SBP) and diastolic (DBP) blood pressure, mean arterial blood pressure (MAP), heart rate (HR), and blood sugar (BS) were measured in three stages: before the injection (M1), at the end of injection (M2), and 10 min after injection (M3). Results: No significant difference observed in SBP, DBP, and MAP at the end of injection and 10 min later. HR was increased significantly after injection and remained significantly higher than baseline after 10 min. BS increased slightly at the end of injection and continued to increase after 10 min. However, changes in BS were not significant. Conclusion: Using two cartridges of epinephrine-containing lidocaine have slight systemic changes in healthy subjects; as a result, this dosage could be used in patients with cardiovascular complications undergoing general anesthesia. |
| first_indexed | 2024-12-11T19:48:37Z |
| format | Article |
| id | doaj.art-91cc326f55484471a92825aedcef59a1 |
| institution | Directory Open Access Journal |
| issn | 2322-4150 2252-0317 |
| language | English |
| last_indexed | 2024-12-11T19:48:37Z |
| publishDate | 2013-01-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Journal of Dental Materials and Techniques |
| spelling | doaj.art-91cc326f55484471a92825aedcef59a12022-12-22T00:52:51ZengMashhad University of Medical SciencesJournal of Dental Materials and Techniques2322-41502252-03172013-01-01211720147Hemodynamic Effect of 2% Lidocaine with 1:80,000 Epinephrine Infiltration in Maxillofacial Surgeries under General AnesthesiaBaratollah Shaban0Elham Moradi1Amir Hossein Nejat2Somayeh Sabzali Zanjanhkhah3Touraj Vaezi4Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Oral and Maxillofacial Radiology, Khorasgan Azad University, Isfahan, IranStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, IranGeneral DentistDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, IranIntroduction: Epinephrine-containing lidocaine is the most used anestheic drug in dentistry. The aim of this study was to investigate the hemodynamic changes following local infiltration of 2%lidocaine with 1:80,000 epinephrine in subjects undergoing orthognatic surgery under general anesthesia. Methods: Twenty five patients without any systemic disease participated. After general anesthesia, two cartridges of 2% lidocaine + 1:80,000 epinephrine were infiltrated around the surgery site. Systolic (SBP) and diastolic (DBP) blood pressure, mean arterial blood pressure (MAP), heart rate (HR), and blood sugar (BS) were measured in three stages: before the injection (M1), at the end of injection (M2), and 10 min after injection (M3). Results: No significant difference observed in SBP, DBP, and MAP at the end of injection and 10 min later. HR was increased significantly after injection and remained significantly higher than baseline after 10 min. BS increased slightly at the end of injection and continued to increase after 10 min. However, changes in BS were not significant. Conclusion: Using two cartridges of epinephrine-containing lidocaine have slight systemic changes in healthy subjects; as a result, this dosage could be used in patients with cardiovascular complications undergoing general anesthesia.http://jdmt.mums.ac.ir/pdf_147_ae0fbd97cceec354d712aa5e7c082686.htmlBlood pressureEpinephrineheart rateLidocainelocal anesthesia |
| spellingShingle | Baratollah Shaban Elham Moradi Amir Hossein Nejat Somayeh Sabzali Zanjanhkhah Touraj Vaezi Hemodynamic Effect of 2% Lidocaine with 1:80,000 Epinephrine Infiltration in Maxillofacial Surgeries under General Anesthesia Journal of Dental Materials and Techniques Blood pressure Epinephrine heart rate Lidocaine local anesthesia |
| title | Hemodynamic Effect of 2% Lidocaine with 1:80,000 Epinephrine Infiltration in Maxillofacial Surgeries under General Anesthesia |
| title_full | Hemodynamic Effect of 2% Lidocaine with 1:80,000 Epinephrine Infiltration in Maxillofacial Surgeries under General Anesthesia |
| title_fullStr | Hemodynamic Effect of 2% Lidocaine with 1:80,000 Epinephrine Infiltration in Maxillofacial Surgeries under General Anesthesia |
| title_full_unstemmed | Hemodynamic Effect of 2% Lidocaine with 1:80,000 Epinephrine Infiltration in Maxillofacial Surgeries under General Anesthesia |
| title_short | Hemodynamic Effect of 2% Lidocaine with 1:80,000 Epinephrine Infiltration in Maxillofacial Surgeries under General Anesthesia |
| title_sort | hemodynamic effect of 2 lidocaine with 1 80 000 epinephrine infiltration in maxillofacial surgeries under general anesthesia |
| topic | Blood pressure Epinephrine heart rate Lidocaine local anesthesia |
| url | http://jdmt.mums.ac.ir/pdf_147_ae0fbd97cceec354d712aa5e7c082686.html |
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