Group B streptococcal infections during pregnancy and perinatal consequences: what do we need to determine more than a bacteriological analysis?

Group B of streptococcal infection is responsible for maternal and fetal morbidity and mortality. Fetal consequences of streptococcal B infection may lead to puerperal sepsis, meningitis, encephalitis or pneumonia. Long-term consequences may determine neurological sequelae and mental disabilities, a...

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Main Authors: Anca A. Simionescu, Ana Maria Alexandra Stanescu
Format: Article
Language:English
Published: Amaltea Medical Publishing House 2021-06-01
Series:Romanian Journal of Infectious Diseases
Subjects:
Online Access:https://rjid.com.ro/articles/2021.2/RJID_2021_2_Art-02.pdf
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author Anca A. Simionescu
Ana Maria Alexandra Stanescu
author_facet Anca A. Simionescu
Ana Maria Alexandra Stanescu
author_sort Anca A. Simionescu
collection DOAJ
description Group B of streptococcal infection is responsible for maternal and fetal morbidity and mortality. Fetal consequences of streptococcal B infection may lead to puerperal sepsis, meningitis, encephalitis or pneumonia. Long-term consequences may determine neurological sequelae and mental disabilities, and very rare are reported cases for the late death of the child. Maternal consequences of streptococcal B infection are endometritis and sepsis. Universal screening and antibioprophylaxy during labour are safe and effective. But, systematic intrapartum prophylaxis for carriers of SGB does not appear to have effects on long-term complications. Also, systematic cultures in neonates do not appear to detect antenatally all carriers of streptococcus B. Herein, we present the particularity of streptococcal infection in pregnancy that may contribute to further strategy. Better laboratory tests for identifying serotypes, genotypes and phenotypes must be available, significantly to differentiate between dtreptococcal high- and low-risk regarding materno-fetal consequences. Immunization remains a promising way to eradicate this infection
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spelling doaj.art-91cf113f3da2490394616a02ccf1c6a42022-12-22T02:21:55ZengAmaltea Medical Publishing HouseRomanian Journal of Infectious Diseases1454-33892069-60512021-06-01242717510.37897/RJID.2021.2.2Group B streptococcal infections during pregnancy and perinatal consequences: what do we need to determine more than a bacteriological analysis?Anca A. Simionescu0Ana Maria Alexandra Stanescu1“Carol Davila“ University of Medicine and Pharmacy, Bucharest, Romania; Filantropia Clinical Hospital, Bucharest, Romania“Carol Davila“ University of Medicine and Pharmacy, Bucharest, RomaniaGroup B of streptococcal infection is responsible for maternal and fetal morbidity and mortality. Fetal consequences of streptococcal B infection may lead to puerperal sepsis, meningitis, encephalitis or pneumonia. Long-term consequences may determine neurological sequelae and mental disabilities, and very rare are reported cases for the late death of the child. Maternal consequences of streptococcal B infection are endometritis and sepsis. Universal screening and antibioprophylaxy during labour are safe and effective. But, systematic intrapartum prophylaxis for carriers of SGB does not appear to have effects on long-term complications. Also, systematic cultures in neonates do not appear to detect antenatally all carriers of streptococcus B. Herein, we present the particularity of streptococcal infection in pregnancy that may contribute to further strategy. Better laboratory tests for identifying serotypes, genotypes and phenotypes must be available, significantly to differentiate between dtreptococcal high- and low-risk regarding materno-fetal consequences. Immunization remains a promising way to eradicate this infectionhttps://rjid.com.ro/articles/2021.2/RJID_2021_2_Art-02.pdfpregnancystreptococcus agalactiaehemolysinimmunologymembranes vesicle
spellingShingle Anca A. Simionescu
Ana Maria Alexandra Stanescu
Group B streptococcal infections during pregnancy and perinatal consequences: what do we need to determine more than a bacteriological analysis?
Romanian Journal of Infectious Diseases
pregnancy
streptococcus agalactiae
hemolysin
immunology
membranes vesicle
title Group B streptococcal infections during pregnancy and perinatal consequences: what do we need to determine more than a bacteriological analysis?
title_full Group B streptococcal infections during pregnancy and perinatal consequences: what do we need to determine more than a bacteriological analysis?
title_fullStr Group B streptococcal infections during pregnancy and perinatal consequences: what do we need to determine more than a bacteriological analysis?
title_full_unstemmed Group B streptococcal infections during pregnancy and perinatal consequences: what do we need to determine more than a bacteriological analysis?
title_short Group B streptococcal infections during pregnancy and perinatal consequences: what do we need to determine more than a bacteriological analysis?
title_sort group b streptococcal infections during pregnancy and perinatal consequences what do we need to determine more than a bacteriological analysis
topic pregnancy
streptococcus agalactiae
hemolysin
immunology
membranes vesicle
url https://rjid.com.ro/articles/2021.2/RJID_2021_2_Art-02.pdf
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