A semi-automated, field-portable microscopy platform for clinical diagnostic applications
Clinical microscopy is a versatile diagnostic platform used for diagnosis of a multitude of diseases. In the recent past, many microfluidics based point-of-care diagnostic devices have been developed, which serve as alternatives to microscopy. However, these point-of-care devices are not as multi-fu...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing LLC
2015-08-01
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| Series: | AIP Advances |
| Online Access: | http://dx.doi.org/10.1063/1.4915133 |
| _version_ | 1818299190851141632 |
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| author | Veerendra Kalyan Jagannadh Rajesh Srinivasan Sai Siva Gorthi |
| author_facet | Veerendra Kalyan Jagannadh Rajesh Srinivasan Sai Siva Gorthi |
| author_sort | Veerendra Kalyan Jagannadh |
| collection | DOAJ |
| description | Clinical microscopy is a versatile diagnostic platform used for diagnosis of a multitude of diseases. In the recent past, many microfluidics based point-of-care diagnostic devices have been developed, which serve as alternatives to microscopy. However, these point-of-care devices are not as multi-functional and versatile as clinical microscopy. With the use of custom designed optics and microfluidics, we have developed a versatile microscopy-based cellular diagnostic platform, which can be used at the point of care. The microscopy platform presented here is capable of detecting infections of very low parasitemia level (in a very small quantity of sample), without the use of any additional computational hardware. Such a cost-effective and portable diagnostic device, would greatly impact the quality of health care available to people living in rural locations of the world. Apart from clinical diagnostics, it’s applicability to field research in environmental microbiology has also been outlined. |
| first_indexed | 2024-12-13T04:47:17Z |
| format | Article |
| id | doaj.art-91cfddeb78184a9b86a68675e7923d7a |
| institution | Directory Open Access Journal |
| issn | 2158-3226 |
| language | English |
| last_indexed | 2024-12-13T04:47:17Z |
| publishDate | 2015-08-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | AIP Advances |
| spelling | doaj.art-91cfddeb78184a9b86a68675e7923d7a2022-12-21T23:59:08ZengAIP Publishing LLCAIP Advances2158-32262015-08-0158084902084902-1010.1063/1.4915133003599ADVA semi-automated, field-portable microscopy platform for clinical diagnostic applicationsVeerendra Kalyan Jagannadh0Rajesh Srinivasan1Sai Siva Gorthi2Optics & Microfluidics Instrumentation Lab, Department of Instrumentation & Applied Physics, Indian Institute of Science (IISc), Bangalore - 560012, IndiaOptics & Microfluidics Instrumentation Lab, Department of Instrumentation & Applied Physics, Indian Institute of Science (IISc), Bangalore - 560012, IndiaOptics & Microfluidics Instrumentation Lab, Department of Instrumentation & Applied Physics, Indian Institute of Science (IISc), Bangalore - 560012, IndiaClinical microscopy is a versatile diagnostic platform used for diagnosis of a multitude of diseases. In the recent past, many microfluidics based point-of-care diagnostic devices have been developed, which serve as alternatives to microscopy. However, these point-of-care devices are not as multi-functional and versatile as clinical microscopy. With the use of custom designed optics and microfluidics, we have developed a versatile microscopy-based cellular diagnostic platform, which can be used at the point of care. The microscopy platform presented here is capable of detecting infections of very low parasitemia level (in a very small quantity of sample), without the use of any additional computational hardware. Such a cost-effective and portable diagnostic device, would greatly impact the quality of health care available to people living in rural locations of the world. Apart from clinical diagnostics, it’s applicability to field research in environmental microbiology has also been outlined.http://dx.doi.org/10.1063/1.4915133 |
| spellingShingle | Veerendra Kalyan Jagannadh Rajesh Srinivasan Sai Siva Gorthi A semi-automated, field-portable microscopy platform for clinical diagnostic applications AIP Advances |
| title | A semi-automated, field-portable microscopy platform for clinical diagnostic applications |
| title_full | A semi-automated, field-portable microscopy platform for clinical diagnostic applications |
| title_fullStr | A semi-automated, field-portable microscopy platform for clinical diagnostic applications |
| title_full_unstemmed | A semi-automated, field-portable microscopy platform for clinical diagnostic applications |
| title_short | A semi-automated, field-portable microscopy platform for clinical diagnostic applications |
| title_sort | semi automated field portable microscopy platform for clinical diagnostic applications |
| url | http://dx.doi.org/10.1063/1.4915133 |
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