Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by <named-content content-type="genus-species">Candida albicans</named-content> Hyphae

Candidalysin Crucially Contributes to Nlrp3 Inflammasome Activation by <named-content content-type="genus-species">Candida albicans</named-content> Hyphae

ABSTRACT Candida albicans is an opportunistic fungal pathogen that can cause life-threatening infections, particularly in immunocompromised patients. C. albicans induced activation of the Nlrp3 inflammasome, leading to secretion of bioactive interleukin 1β (IL-1β) is a crucial myeloid cell immune re...

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Bibliographic Details
Main Authors: Ona Rogiers, Ulrika C. Frising, Soňa Kucharíková, Mary Ann Jabra-Rizk, Geert van Loo, Patrick Van Dijck, Andy Wullaert
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mBio
Subjects:
Candida albicans
NLRP3
candidalysin
inflammasome
primary macrophages
Online Access:https://journals.asm.org/doi/10.1128/mBio.02221-18

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