Epidemiology of Human Mycobacterium bovis Disease, California, USA, 2003–2011
We conducted a retrospective review of California tuberculosis (TB) registry and genotyping data to evaluate trends, analyze epidemiologic differences between adult and child case-patients with Mycobacterium bovis disease, and identify risk factors for M. bovis disease. The percentage of TB cases at...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2015-03-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/21/3/14-1539_article |
| _version_ | 1818504791260659712 |
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| author | Mark Gallivan Neha Shah Jennifer Flood |
| author_facet | Mark Gallivan Neha Shah Jennifer Flood |
| author_sort | Mark Gallivan |
| collection | DOAJ |
| description | We conducted a retrospective review of California tuberculosis (TB) registry and genotyping data to evaluate trends, analyze epidemiologic differences between adult and child case-patients with Mycobacterium bovis disease, and identify risk factors for M. bovis disease. The percentage of TB cases attributable to M. bovis increased from 3.4% (80/2,384) in 2003 to 5.4% (98/1,808) in 2011 (p = 0.002). All (6/6) child case-patients with M. bovis disease during 2010–2011 had >1 parent/guardian who was born in Mexico, compared with 38% (22/58) of child case-patients with M. tuberculosis disease (p = 0.005). Multivariate analysis of TB case-patients showed Hispanic ethnicity, extrapulmonary disease, diabetes, and immunosuppressive conditions, excluding HIV co-infection, were independently associated with M. bovis disease. Prevention efforts should focus on Hispanic binational families and adults with immunosuppressive conditions. Collection of additional risk factors in the national TB surveillance system and expansion of whole-genome sequencing should be considered. |
| first_indexed | 2024-12-10T21:42:02Z |
| format | Article |
| id | doaj.art-91db1b5e19ce4c0aaebd06adc975b983 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-10T21:42:02Z |
| publishDate | 2015-03-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-91db1b5e19ce4c0aaebd06adc975b9832022-12-22T01:32:28ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592015-03-0121343544310.3201/eid2103.141539Epidemiology of Human Mycobacterium bovis Disease, California, USA, 2003–2011Mark GallivanNeha ShahJennifer FloodWe conducted a retrospective review of California tuberculosis (TB) registry and genotyping data to evaluate trends, analyze epidemiologic differences between adult and child case-patients with Mycobacterium bovis disease, and identify risk factors for M. bovis disease. The percentage of TB cases attributable to M. bovis increased from 3.4% (80/2,384) in 2003 to 5.4% (98/1,808) in 2011 (p = 0.002). All (6/6) child case-patients with M. bovis disease during 2010–2011 had >1 parent/guardian who was born in Mexico, compared with 38% (22/58) of child case-patients with M. tuberculosis disease (p = 0.005). Multivariate analysis of TB case-patients showed Hispanic ethnicity, extrapulmonary disease, diabetes, and immunosuppressive conditions, excluding HIV co-infection, were independently associated with M. bovis disease. Prevention efforts should focus on Hispanic binational families and adults with immunosuppressive conditions. Collection of additional risk factors in the national TB surveillance system and expansion of whole-genome sequencing should be considered.https://wwwnc.cdc.gov/eid/article/21/3/14-1539_articleTuberculosisMycobacterium bovissurveillanceepidemiologytrendszoonoses |
| spellingShingle | Mark Gallivan Neha Shah Jennifer Flood Epidemiology of Human Mycobacterium bovis Disease, California, USA, 2003–2011 Emerging Infectious Diseases Tuberculosis Mycobacterium bovis surveillance epidemiology trends zoonoses |
| title | Epidemiology of Human Mycobacterium bovis Disease, California, USA, 2003–2011 |
| title_full | Epidemiology of Human Mycobacterium bovis Disease, California, USA, 2003–2011 |
| title_fullStr | Epidemiology of Human Mycobacterium bovis Disease, California, USA, 2003–2011 |
| title_full_unstemmed | Epidemiology of Human Mycobacterium bovis Disease, California, USA, 2003–2011 |
| title_short | Epidemiology of Human Mycobacterium bovis Disease, California, USA, 2003–2011 |
| title_sort | epidemiology of human mycobacterium bovis disease california usa 2003 2011 |
| topic | Tuberculosis Mycobacterium bovis surveillance epidemiology trends zoonoses |
| url | https://wwwnc.cdc.gov/eid/article/21/3/14-1539_article |
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