Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy

Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy

Current therapeutics options for viral myocarditis are unsatisfactory. Melatonin (MLT), a hormone secreted by the pineal gland and other organs, has protective effects on ischemic heart injury. However, the potential therapeutic effect of MLT on viral myocarditis is unknown. In this study, we invest...

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Bibliographic Details
Main Authors: Yimiao Sang, Xiaohong Gu, Lulu Pan, Chunxiang Zhang, Xing Rong, Tingting Wu, Tianhe Xia, Yuechun Li, Lisha Ge, Yuanhai Zhang, Maoping Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Pharmacology
Subjects:
myocarditis
melatonin
autophagy
apoptosis
coxsackievirus B3
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01384/full

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