Induced acute hyperglycemia modifies the barrier function of the intestinal epithelium by tissue inflammation and tight junction disruption resulting in hydroelectrolytic secretion in an animal model

Induced acute hyperglycemia modifies the barrier function of the intestinal epithelium by tissue inflammation and tight junction disruption resulting in hydroelectrolytic secretion in an animal model

Abstract Diabetic-metabolic syndrome (MetS-D) has a high prevalence worldwide, in which an association with the rupture of the intestinal epithelium barrier function (IEBF) has been pointed out, but the functional and morphological properties are still not well understood. This study aimed to evalua...

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Bibliographic Details
Main Authors: F.J.W.S. Siqueira, F.A.P. Rodrigues, S.A. Ribeiro, H.N. Veras, F.C.S. Ferreira, R.C.L. Siqueira, A.A. dos Santos, A. Havt, A.A.M. Lima
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2024-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Diabetic metabolic syndrome
Intestinal epithelium barrier function
Tight junctions
Oxidative damage
Ion and water intestinal transports
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2024000100626&lng=en&tlng=en

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