Design and validation of DNA libraries for multiplexing proximity ligation assays.

Design and validation of DNA libraries for multiplexing proximity ligation assays.

Here, we present an in silico, analytical procedure for designing and testing orthogonal DNA templates for multiplexing of the proximity ligation assay (PLA). PLA is a technology for the detection of protein interactions, post-translational modifications, and protein concentrations. To enable multip...

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Bibliographic Details
Main Authors:	Nicolas Gobet, Simon Ketterer, Matthias Meier
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4227721?pdf=render

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