Dioscin suppresses proliferation and metastasis of osteosarcoma by inhibiting HuR/Pim1 axis via the induction of miR-16-5p level

Dioscin suppresses proliferation and metastasis of osteosarcoma by inhibiting HuR/Pim1 axis via the induction of miR-16-5p level

Dioscin (DS) is a natural compound with inhibitory effects on multiple cancer types and we explored the mechanism driving the antagonizing effect of DS on osteosarcoma (OS). OS cell lines were treated with DS and microRNAs (miRs) responding to DS treatment were determined. Effects of DS on viability...

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Bibliographic Details
Main Authors: Bo Jiang, Xinsheng Fu, Qichuan Zhang, Yunfei Du
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Functional Foods
Subjects:
Dioscin
miR-16-5p
Osteosarcoma
HuR
Pim1
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622003292

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