The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature
Abstract The relationship between chronic myelogenous leukemia (CML) and tuberous sclerosis (TS) is unusual and uncommon. Here, we report a 24‐year‐old woman diagnosed with TS and later identified with CML, as the second case reported with such coexistence, treated with Nilotinib. This article propo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-03-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.7087 |
| _version_ | 1797856093547790336 |
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| author | Abdulrahman Al‐Abdulmalek Reem Al‐Suliman Mohammad Abu‐Tineh Mostafa Ali Mohamed A. Yassin |
| author_facet | Abdulrahman Al‐Abdulmalek Reem Al‐Suliman Mohammad Abu‐Tineh Mostafa Ali Mohamed A. Yassin |
| author_sort | Abdulrahman Al‐Abdulmalek |
| collection | DOAJ |
| description | Abstract The relationship between chronic myelogenous leukemia (CML) and tuberous sclerosis (TS) is unusual and uncommon. Here, we report a 24‐year‐old woman diagnosed with TS and later identified with CML, as the second case reported with such coexistence, treated with Nilotinib. This article proposes a hypothesis to explain the association. Therefore, we propose Nilotinib for the treatment of patients with such coexisting diseases. Further studies are warranted to reveal the dynamics between these conditions. |
| first_indexed | 2024-04-09T20:35:51Z |
| format | Article |
| id | doaj.art-91e468329b24477c9775e1cf0bffb327 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-04-09T20:35:51Z |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-91e468329b24477c9775e1cf0bffb3272023-03-30T10:21:25ZengWileyClinical Case Reports2050-09042023-03-01113n/an/a10.1002/ccr3.7087The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literatureAbdulrahman Al‐Abdulmalek0Reem Al‐Suliman1Mohammad Abu‐Tineh2Mostafa Ali3Mohamed A. Yassin4Department of Internal Medicine Hamad Medical Corporation Doha QatarDepartment of Medical Oncology National Center for Cancer Care and Research Doha QatarDepartment of Medical Oncology National Center for Cancer Care and Research Doha QatarDepartment of Radiology Hamad Medical Corporation Doha QatarDepartment of Medical Oncology National Center for Cancer Care and Research Doha QatarAbstract The relationship between chronic myelogenous leukemia (CML) and tuberous sclerosis (TS) is unusual and uncommon. Here, we report a 24‐year‐old woman diagnosed with TS and later identified with CML, as the second case reported with such coexistence, treated with Nilotinib. This article proposes a hypothesis to explain the association. Therefore, we propose Nilotinib for the treatment of patients with such coexisting diseases. Further studies are warranted to reveal the dynamics between these conditions.https://doi.org/10.1002/ccr3.7087CMLtuberous sclerosistyrosine kinase inhibitors |
| spellingShingle | Abdulrahman Al‐Abdulmalek Reem Al‐Suliman Mohammad Abu‐Tineh Mostafa Ali Mohamed A. Yassin The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature Clinical Case Reports CML tuberous sclerosis tyrosine kinase inhibitors |
| title | The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature |
| title_full | The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature |
| title_fullStr | The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature |
| title_full_unstemmed | The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature |
| title_short | The effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis. A case report and review of literature |
| title_sort | effectiveness of tyrosine kinase inhibitor for chronic myeloid leukemia in tuberous sclerosis a case report and review of literature |
| topic | CML tuberous sclerosis tyrosine kinase inhibitors |
| url | https://doi.org/10.1002/ccr3.7087 |
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