Giant Intramural Hematoma of the Colon in Acquired Factor VIII Inhibitor
Intramural hematoma of the colon is very rare, particularly when associated with the development of autoantibodies against factor VIII. We report a case of a 66-year-old man with abdominal pain, hematochezia and clots in the left colon, without any radiologic signs of active bleeding or bowel occlu...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Ordem dos Médicos
2019-09-01
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| Series: | Acta Médica Portuguesa |
| Subjects: | |
| Online Access: | https://actamedicaportuguesa.com/revista/index.php/amp/article/view/8519 |
| _version_ | 1811228290327773184 |
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| author | Joana Figueiredo Nuno Borges José Pascoalinho Ricardo Matos |
| author_facet | Joana Figueiredo Nuno Borges José Pascoalinho Ricardo Matos |
| author_sort | Joana Figueiredo |
| collection | DOAJ |
| description |
Intramural hematoma of the colon is very rare, particularly when associated with the development of autoantibodies against factor VIII.
We report a case of a 66-year-old man with abdominal pain, hematochezia and clots in the left colon, without any radiologic signs of active bleeding or bowel occlusion or analytical changes in routine coagulation screening, but with positive autoantibodies against factor VIII. The clinical instability prompted surgical exploration. An intramural hematoma of the left colon was found, and a left colectomy was performed. The patient was treated with hemoderivatives and corticosteroids with clinical improvement. The diagnosis of spontaneous intramural hematoma might be a challenge, particularly in the absence of clinical suspicion. An early recognition is essential for a positive outcome. This case highlights a rare cause of bleeding and intestinal obstruction, but also the difficulty and relevance of establishing a clinical diagnosis when diagnostic tests are not completely informative.
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| first_indexed | 2024-04-12T09:55:38Z |
| format | Article |
| id | doaj.art-91e563235c8f40b294997c6ec78b835b |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-12T09:55:38Z |
| publishDate | 2019-09-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-91e563235c8f40b294997c6ec78b835b2022-12-22T03:37:43ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582019-09-0132910.20344/amp.85194820Giant Intramural Hematoma of the Colon in Acquired Factor VIII InhibitorJoana Figueiredo0Nuno Borges1José Pascoalinho2Ricardo Matos3Department of General Surgery. Centro Hospitalar Universitário de Lisboa Central. Lisboa.Department of General Surgery. Centro Hospitalar Universitário de Lisboa Central. Lisboa.Department of General Surgery. Centro Hospitalar Universitário de Lisboa Central. Lisboa.Department of General Surgery. Centro Hospitalar Universitário de Lisboa Central. Lisboa. Intramural hematoma of the colon is very rare, particularly when associated with the development of autoantibodies against factor VIII. We report a case of a 66-year-old man with abdominal pain, hematochezia and clots in the left colon, without any radiologic signs of active bleeding or bowel occlusion or analytical changes in routine coagulation screening, but with positive autoantibodies against factor VIII. The clinical instability prompted surgical exploration. An intramural hematoma of the left colon was found, and a left colectomy was performed. The patient was treated with hemoderivatives and corticosteroids with clinical improvement. The diagnosis of spontaneous intramural hematoma might be a challenge, particularly in the absence of clinical suspicion. An early recognition is essential for a positive outcome. This case highlights a rare cause of bleeding and intestinal obstruction, but also the difficulty and relevance of establishing a clinical diagnosis when diagnostic tests are not completely informative. https://actamedicaportuguesa.com/revista/index.php/amp/article/view/8519ColonHematomaHemophilia AFactor VIII |
| spellingShingle | Joana Figueiredo Nuno Borges José Pascoalinho Ricardo Matos Giant Intramural Hematoma of the Colon in Acquired Factor VIII Inhibitor Acta Médica Portuguesa Colon Hematoma Hemophilia A Factor VIII |
| title | Giant Intramural Hematoma of the Colon in Acquired Factor VIII Inhibitor |
| title_full | Giant Intramural Hematoma of the Colon in Acquired Factor VIII Inhibitor |
| title_fullStr | Giant Intramural Hematoma of the Colon in Acquired Factor VIII Inhibitor |
| title_full_unstemmed | Giant Intramural Hematoma of the Colon in Acquired Factor VIII Inhibitor |
| title_short | Giant Intramural Hematoma of the Colon in Acquired Factor VIII Inhibitor |
| title_sort | giant intramural hematoma of the colon in acquired factor viii inhibitor |
| topic | Colon Hematoma Hemophilia A Factor VIII |
| url | https://actamedicaportuguesa.com/revista/index.php/amp/article/view/8519 |
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