Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction

Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction

TAR DNA-binding protein 43 (TDP-43) is a member of an evolutionarily conserved family of heterogeneous nuclear ribonucleoproteins that modulate multiple steps in RNA metabolic processes. Cytoplasmic aggregation of TDP-43 in affected neurons is a pathological hallmark of many neurodegenerative diseas...

Bibliografske podrobnosti
Main Authors:	Yu-Mi Jeon, Younghwi Kwon, Shinrye Lee, Seyeon Kim, Myungjin Jo, Seongsoo Lee, Sang Ryong Kim, Kiyoung Kim, Hyung-Jun Kim
Format:	Article
Jezik:	English
Izdano:	MDPI AG 2021-12-01
Serija:	Antioxidants
Teme:	TAR DNA-binding protein 43 amyotrophic lateral sclerosis <i>Drosophila</i> mitochondrial dysfunction oxidative stress
Online dostop:	https://www.mdpi.com/2076-3921/11/1/82

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