Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction

Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction

TAR DNA-binding protein 43 (TDP-43) is a member of an evolutionarily conserved family of heterogeneous nuclear ribonucleoproteins that modulate multiple steps in RNA metabolic processes. Cytoplasmic aggregation of TDP-43 in affected neurons is a pathological hallmark of many neurodegenerative diseas...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Yu-Mi Jeon, Younghwi Kwon, Shinrye Lee, Seyeon Kim, Myungjin Jo, Seongsoo Lee, Sang Ryong Kim, Kiyoung Kim, Hyung-Jun Kim
التنسيق:	مقال
اللغة:	English
منشور في:	MDPI AG 2021-12-01
سلاسل:	Antioxidants
الموضوعات:	TAR DNA-binding protein 43 amyotrophic lateral sclerosis <i>Drosophila</i> mitochondrial dysfunction oxidative stress
الوصول للمادة أونلاين:	https://www.mdpi.com/2076-3921/11/1/82

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