Predictive and prognostic impact of ferroptosis-related genes ACSL4 and GPX4 on breast cancer treated with neoadjuvant chemotherapy

Predictive and prognostic impact of ferroptosis-related genes ACSL4 and GPX4 on breast cancer treated with neoadjuvant chemotherapy

Background: Recent evidence shows that inducing ferroptosis may improve efficacy of tumor therapy. However, ferroptosis-related genes have been little studied in patients with breast cancer especially in the neoadjuvant setting. ACSL4 and GPX4 have been well established as the positive and negative...

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Bibliographic Details
Main Authors: Rui Sha, Yaqian Xu, Chenwei Yuan, Xiaonan Sheng, Ziping Wu, Jing Peng, Yaohui Wang, Yanping Lin, Liheng Zhou, Shuguang Xu, Jie Zhang, Wenjin Yin, Jinsong Lu
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:EBioMedicine
Subjects:
Breast cancer
Neoadjuvant chemotherapy
Pathological complete response
Ferroptosis
ACSL4
GPX4
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421003534

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