A single-amino-acid substitution in the HA protein changes the replication and pathogenicity of the 2009 pandemic A (H1N1) influenza viruses <it>in vitro </it>and <it>in vivo</it>

A single-amino-acid substitution in the HA protein changes the replication and pathogenicity of the 2009 pandemic A (H1N1) influenza viruses <it>in vitro </it>and <it>in vivo</it>

<p>Abstract</p> <p>Background</p> <p>The novel pandemic A (H1N1) virus was first identified in Mexico in April 2009 and since then it spread world wide over a short period of time. Although the virus infection is generally associated with mild disease and a relatively l...

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Bibliographic Details
Main Authors: Ma Chunmei, Zhu Hua, Zhan Lingjun, Li Fengdi, Ma Yila, Deng Wei, Lv Qi, Bao Linlin, Xu Lili, Qin Chuan
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Virology Journal
Online Access:http://www.virologyj.com/content/7/1/325

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