Systems biology approaches to investigate the role of granulomas in TB-HIV coinfection

The risk of active tuberculosis disease is 15-21 times higher in those coinfected with human immunodeficiency virus-1 (HIV) compared to tuberculosis alone, and tuberculosis is the leading cause of death in HIV+ individuals. Mechanisms driving synergy between Mycobacterium tuberculosis (Mtb) and HIV...

Full description

Bibliographic Details
Main Authors: Alexis Hoerter, Eusondia Arnett, Larry S. Schlesinger, Elsje Pienaar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1014515/full